Ruthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination

dc.creatorTan, Eric
dc.creatorKonovalov, Andrey I.
dc.creatorFernandez, Gabriela Araceli
dc.creatorDorel, Ruth
dc.creatorEchavarren, Antonio M.
dc.date.accessioned2018-06-28T14:05:07Z
dc.date.accessioned2018-11-06T12:55:37Z
dc.date.available2018-06-28T14:05:07Z
dc.date.available2018-11-06T12:55:37Z
dc.date.created2018-06-28T14:05:07Z
dc.date.issued2017-10
dc.identifierTan, Eric; Konovalov, Andrey I.; Fernandez, Gabriela Araceli; Dorel, Ruth; Echavarren, Antonio M.; Ruthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination; American Chemical Society; Organic Letters; 19; 20; 10-2017; 5561-5564
dc.identifier1523-7060
dc.identifierhttp://hdl.handle.net/11336/50324
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1871239
dc.description.abstractThe alkynylation of naphthols takes place with total regiocontrol at the peri position of the hydroxyl group in the presence of [RuCl2(p-cymene)]2 as the catalyst. This reaction features high functional group tolerance. The related ortho-alkynylation of benzoic acids proceeds under similar conditions and also shows wide functional group tolerance. Both reactions proceed through metalation, insertion of the alkyne, and bromide elimination.
dc.languageeng
dc.publisherAmerican Chemical Society
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/abs/10.1021/acs.orglett.7b02655
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1021/acs.orglett.7b02655
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679662/
dc.rightshttps://creativecommons.org/licenses/by/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectRuthenium catalyst
dc.subjectAlkynylation
dc.subjectNaphtols
dc.subjectBenzoic acids
dc.titleRuthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución