Pharmacotherapy with 17β-estradiol and progesterone prevents development of mouse experimental autoimmune encephalomyelitis

dc.creatorGaray, Laura Ines
dc.creatorGonzalez Deniselle, Maria Claudia
dc.creatorGierman, Lobke
dc.creatorLima, Analia Ethel
dc.creatorRoig, Paulina
dc.creatorde Nicola, Alejandro Federico
dc.date.accessioned2017-03-27T18:59:18Z
dc.date.accessioned2018-11-06T12:36:28Z
dc.date.available2017-03-27T18:59:18Z
dc.date.available2018-11-06T12:36:28Z
dc.date.created2017-03-27T18:59:18Z
dc.date.issued2010-01-01
dc.identifierGaray, Laura Ines; Gonzalez Deniselle, Maria Claudia; Gierman, Lobke; Lima, Analia Ethel; Roig, Paulina; et al.; Pharmacotherapy with 17β-estradiol and progesterone prevents development of mouse experimental autoimmune encephalomyelitis; De Gruyter; Hormone Molecular Biology and Clinical Investigation; 1; 1; 1-1-2010; 43-51
dc.identifier1868-1883
dc.identifierhttp://hdl.handle.net/11336/14286
dc.identifier1868-1891
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1868225
dc.description.abstractPregnant women with multiple sclerosis (MS) show disease remission in the third trimester concomitant with high circulating levels of sex steroids. Rodent experimental autoimmune encephalomyelitis (EAE) is an accepted model for MS. Previous studies have shown that monotherapy with estrogens or progesterone exert beneficial effects on EAE. The aim of the present study was to determine if estrogen and progesterone cotherapy of C57BL/6 female mice provided substantial protection from EAE.
dc.languageeng
dc.publisherDe Gruyter
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.degruyter.com/view/j/hmbci.2010.1.issue-1/hmbci.2010.006/hmbci.2010.006.xml
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://doi.org/10.1515/hmbci.2010.006
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectMULTIPLE SCLEROSIS
dc.subjectPROGESTERONE
dc.subjectESTRADIOL
dc.subjectEXPERIMENTA AUTOIMMUNE ENCEPHALOMYELITIS
dc.subjectMYELINATION
dc.titlePharmacotherapy with 17β-estradiol and progesterone prevents development of mouse experimental autoimmune encephalomyelitis
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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