Regio-specific synthesis of new 1-(tert-butyl)-1H-pyrazolecarboxamide derivatives

dc.creatorRuatta Merke, Santiago Matías
dc.creatorMurguia, Marcelo Cesar
dc.creatorRamírez de Arellano, Carmen
dc.creatorFustero, Santos
dc.date.accessioned2018-08-15T18:10:32Z
dc.date.accessioned2018-11-06T12:26:47Z
dc.date.available2018-08-15T18:10:32Z
dc.date.available2018-11-06T12:26:47Z
dc.date.created2018-08-15T18:10:32Z
dc.date.issued2017-06
dc.identifierRuatta Merke, Santiago Matías; Murguia, Marcelo Cesar; Ramírez de Arellano, Carmen; Fustero, Santos; Regio-specific synthesis of new 1-(tert-butyl)-1H-pyrazolecarboxamide derivatives; Pergamon-Elsevier Science Ltd; Tetrahedron Letters; 58; 25; 6-2017; 2441-2444
dc.identifier0040-4039
dc.identifierhttp://hdl.handle.net/11336/55666
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1866713
dc.description.abstractRegio-specific and non-regiospecific condensation reactions on 1,3-dicarbonyl compounds rendered 1,3,5-trisubstituted pyrazoles. Herein, the control of regio-specificity was a significant improvement in pyrazole research. A high yield acylation of poorly nucleophilic aryl amines, which resulted in mono- or diacylated products depending on the reaction conditions, is described. As a result, a library of potentially bioactive compounds was obtained.
dc.languageeng
dc.publisherPergamon-Elsevier Science Ltd
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.tetlet.2017.05.029
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S004040391730607X
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectARYLAMINE ACYLATION
dc.subjectDIACYLATION
dc.subjectPYRAZOLE CARBOXAMIDE
dc.subjectREGIO-SPECIFIC CONDENSATION
dc.subjectTERT-BUTYL HYDRAZINE
dc.titleRegio-specific synthesis of new 1-(tert-butyl)-1H-pyrazolecarboxamide derivatives
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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