Molecularly Imprinted Solid Phase Extraction Before Capillary Electrophoresis for the Analysis of Estrogens in Serum Samples

dc.creatorContin, Mario Daniel
dc.creatorFlor, Sabrina Andrea
dc.creatorLucangioli, Silvia Edith
dc.creatorTripodi, Valeria Paula
dc.date.accessioned2017-12-13T20:20:47Z
dc.date.available2017-12-13T20:20:47Z
dc.date.created2017-12-13T20:20:47Z
dc.date.issued2014-12
dc.identifierContin, Mario Daniel; Flor, Sabrina Andrea; Lucangioli, Silvia Edith; Tripodi, Valeria Paula; Molecularly Imprinted Solid Phase Extraction Before Capillary Electrophoresis for the Analysis of Estrogens in Serum Samples; Bentham Science Publishers; Current Analytical Chemistry; 10; 2; 12-2014; 235-240
dc.identifier1573-4110
dc.identifierhttp://hdl.handle.net/11336/30526
dc.identifier1875-6727
dc.identifierCONICET Digital
dc.identifierCONICET
dc.description.abstractAn estrogen selected molecular imprinted polymer (MIP) has been developed to be used as an alternative sorbent in solid phase extraction of serum samples before capillary electrophoresis analysis. Following a heat polymerization, MIP has been synthesized using methacrylic acid (MAA) as functional monomer, ethyleneglycol dimethacrylate (EGDMA) as crosslinker, benzoyl peroxide as radical initiator and 17β- estradiol as template, and toluene as porogen. The optimized molecular imprinted solid phase extraction (MISPE) was compared to traditional C18 solid phase extraction to purify estrogens from complex matrices. It was concluded that the MISPE system developed is useful for the selective extraction of 17β- estradiol and its major natural related estrogens, estriol and estrone, from serum samples with minimal interferences and high recoveries.
dc.languageeng
dc.publisherBentham Science Publishers
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/111746
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2174/15734110113090990027
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectEstrogens
dc.subjectMolecular Imprinting
dc.subjectSolid Phase Extraction
dc.subjectSerum
dc.subjectCapillary Electrophoresis
dc.titleMolecularly Imprinted Solid Phase Extraction Before Capillary Electrophoresis for the Analysis of Estrogens in Serum Samples
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


Este ítem pertenece a la siguiente institución