dc.creator | Turk, Gabriela Julia Ana | |
dc.creator | Carobene, Mauricio | |
dc.date.accessioned | 2018-06-06T14:32:54Z | |
dc.date.available | 2018-06-06T14:32:54Z | |
dc.date.created | 2018-06-06T14:32:54Z | |
dc.date.issued | 2015-03 | |
dc.identifier | Turk, Gabriela Julia Ana; Carobene, Mauricio; Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression; Elsevier; EBioMedicine; 2; 3; 3-2015; 188-189 | |
dc.identifier | 2352-3964 | |
dc.identifier | http://hdl.handle.net/11336/47455 | |
dc.identifier | CONICET Digital | |
dc.identifier | CONICET | |
dc.description.abstract | Extreme genetic variability is the hallmark of HIV‐1 infection and itrepresents a major challenge for antiviral treatment and vaccine development.HIV‐1 group M dominates the global pandemic. This genetic diversity not only affects viral epidemiology but it is also linked to the mechanisms used by the virus to escape the patients´ natural humoral and cellular immune responses as well as antiretroviral drug´s action, thus precluding viral control. As a result, monitoring the genetic diversity of HIV‐1 and understanding its consequences onviral fitness is crucial to control the spread of the epidemic | |
dc.language | eng | |
dc.publisher | Elsevier | |
dc.relation | info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.ebiom.2015.02.011 | |
dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2352396415000596 | |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Hiv | |
dc.subject | Recombination | |
dc.subject | Fitness | |
dc.subject | Disease | |
dc.title | Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression | |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:ar-repo/semantics/artículo | |
dc.type | info:eu-repo/semantics/publishedVersion | |