Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression

dc.creatorTurk, Gabriela Julia Ana
dc.creatorCarobene, Mauricio
dc.date.accessioned2018-06-06T14:32:54Z
dc.date.available2018-06-06T14:32:54Z
dc.date.created2018-06-06T14:32:54Z
dc.date.issued2015-03
dc.identifierTurk, Gabriela Julia Ana; Carobene, Mauricio; Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression; Elsevier; EBioMedicine; 2; 3; 3-2015; 188-189
dc.identifier2352-3964
dc.identifierhttp://hdl.handle.net/11336/47455
dc.identifierCONICET Digital
dc.identifierCONICET
dc.description.abstractExtreme genetic variability is the hallmark of HIV‐1 infection and itrepresents a major challenge for antiviral treatment and vaccine development.HIV‐1 group M dominates the global pandemic. This genetic diversity not only affects viral epidemiology but it is also linked to the mechanisms used by the virus to escape the patients´ natural humoral and cellular immune responses as well as antiretroviral drug´s action, thus precluding viral control. As a result, monitoring the genetic diversity of HIV‐1 and understanding its consequences onviral fitness is crucial to control the spread of the epidemic
dc.languageeng
dc.publisherElsevier
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.ebiom.2015.02.011
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2352396415000596
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHiv
dc.subjectRecombination
dc.subjectFitness
dc.subjectDisease
dc.titleDeciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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