Immune-related gene expression in nurse honey bees (Apis mellifera) exposed to synthetic acaricides

dc.creatorGarrido, Paula Melisa
dc.creatorAntúnez, Karina
dc.creatorMartin, Mariana Laura
dc.creatorPorrini, Martín Pablo
dc.creatorZunino, Pablo
dc.creatorEguaras, Martin Javier
dc.date2013-02
dc.identifierhttp://hdl.handle.net/11336/25140
dc.identifierGarrido, Paula Melisa; Antúnez, Karina; Martin, Mariana Laura; Porrini, Martín Pablo; Zunino, Pablo; et al.; Immune-related gene expression in nurse honey bees (Apis mellifera) exposed to synthetic acaricides; Pergamon-Elsevier Science Ltd.; Journal of Insect Physiology; 59; 1; 2-2013; 113-119
dc.identifier0022-1910
dc.identifierCONICET Digital
dc.identifierCONICET
dc.descriptionThe mite Varroa destructor is an ectoparasite affecting honey bees worldwide. Synthetic acaricides have been among the principal tools available to beekeepers for its control, although several studies have shown its negative effects on honey bee physiology. Recent research suggests that those molecules strongly impact on immune signaling cascades and cellular immunity. In the present work, LC50 in six-day-old bees were determined for the following acaricides: tau-fluvalinate, flumethrin, amitraz and coumaphos. According to this obtained value, a group of individuals was treated with each acaricide and then processed for qPCR analysis. Transcript levels for genes encoding antimicrobial peptides and immune-related proteins were assessed. Flumethrin increased the expression of hymenoptaecin when comparing treated and control bees. Significant differences were recorded between coumaphos and flumethrin treatments, while the first one reduced the expression of hymenoptaecin and abaecin, the last one up-regulated their expressions. No significant statistically changes were recorded in the expression levels of vitellogenin, lysozyme or glucose dehydrogenase among bees treated with acaricides and control bees. This work constitutes the first report, under laboratory conditions, about induction of immune related genes in response to synthetic miticides.
dc.descriptionFil: Garrido, Paula Melisa. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
dc.descriptionFil: Antúnez, Karina. Instituto de Investigaciones Biológicas "Clemente Estable"; Uruguay
dc.descriptionFil: Martin, Mariana Laura. Fundación para Investigaciones Biológicas Aplicadas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.descriptionFil: Porrini, Martín Pablo. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
dc.descriptionFil: Zunino, Pablo. Instituto de Investigaciones Biológicas "Clemente Estable"; Uruguay
dc.descriptionFil: Eguaras, Martin Javier. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
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dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherPergamon-Elsevier Science Ltd.
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jinsphys.2012.10.019
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0022191012002727
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subjectApis Mellifera
dc.subjectSynthetic Acaricides
dc.subjectImmune Related Genes
dc.subjectLc50
dc.subjecthttps://purl.org/becyt/ford/1.6
dc.subjecthttps://purl.org/becyt/ford/1
dc.titleImmune-related gene expression in nurse honey bees (Apis mellifera) exposed to synthetic acaricides
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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