Artículos de revistas
Molecular characteristics of mcr-1-carrying plasmids and new mcr-1 variant recovered from polyclonal clinical Escherichia coli from Argentina and Canada
Fecha
2017-07Registro en:
Tijet, Nathalie; Faccone, Diego Francisco; Rapoport, Melina; Seah, Christine; Pasteran, Fernando; et al.; Molecular characteristics of mcr-1-carrying plasmids and new mcr-1 variant recovered from polyclonal clinical Escherichia coli from Argentina and Canada; Public Library of Science; Plos One; 12; 7; 7-2017; 1-13; e0180347
1932-6203
CONICET Digital
CONICET
Autor
Tijet, Nathalie
Faccone, Diego Francisco
Rapoport, Melina
Seah, Christine
Pasteran, Fernando
Ceriana, Paola
Albornoz, Ezequiel Pablo
Corso, Alejandra
Petroni, Alejandro
Melano, Roberto G.
Resumen
Tijet N. and Faccone D. contributed equally to this work.We have characterized nine mcr-1-harboring plasmids from clinical Escherichia coli isolatespreviously described in Argentina and Canada. Three of these plasmids carried a mcr-1-variantcalled here mcr-1.5. All these E. coli isolates were not clonally related and were recoveredin different years and locations. However, their mcr-1-harboring plasmids showed highidentity among them and to others characterized in other countries, which strongly suggeststhat this plasmid-type is playing an important role in spreading this mechanism of resistanceto polymyxins.