Methicillin-resistant Staphylococcus aureus ST30-SCCmec IVc clone as the major cause of community-acquired invasive infections in Argentina

Methicillin-resistant Staphylococcus aureus ST30-SCCmec IVc clone as the major cause of community-acquired invasive infections in Argentina

dc.creatorFernandez, Silvina
dc.creatorFernandez, Silvina
dc.creatorde Vedia, Luis Alberto
dc.creatorde Vedia, Luis Alberto
dc.creatorLopez Furst, M, J.
dc.creatorLopez Furst, M, J.
dc.creatorGardella, Noella Mariel
dc.creatorGardella, Noella Mariel
dc.creatorDi Gregorio, Sabrina Noelia
dc.creatorDi Gregorio, Sabrina Noelia
dc.creatorGanaha, M. C.
dc.creatorGanaha, M. C.
dc.creatorPrieto, S.
dc.creatorPrieto, S.
dc.creatorCarbone, E.
dc.creatorCarbone, E.
dc.creatorLista, N.
dc.creatorLista, N.
dc.creatorRotrying, F.
dc.creatorRotrying, F.
dc.creatorStryjewski, M. D.
dc.creatorStryjewski, M. D.
dc.creatorMollerach, Marta Eugenia
dc.creatorMollerach, Marta Eugenia
dc.date2013-01-20
dc.date2013-01-20
dc.identifierhttp://hdl.handle.net/11336/1712
dc.identifierFernandez, Silvina; de Vedia, Luis Alberto; Lopez Furst, M, J.; Gardella, Noella Mariel; Di Gregorio, Sabrina Noelia; et al.; Methicillin-resistant Staphylococcus aureus ST30-SCCmec IVc clone as the major cause of community-acquired invasive infections in Argentina; Elsevier; Infection, Genetics and Evolution; 14; 20-1-2013; 401-405
dc.identifierFernandez, Silvina; de Vedia, Luis Alberto; Lopez Furst, M, J.; Gardella, Noella Mariel; Di Gregorio, Sabrina Noelia; et al.; Methicillin-resistant Staphylococcus aureus ST30-SCCmec IVc clone as the major cause of community-acquired invasive infections in Argentina; Elsevier; Infection, Genetics and Evolution; 14; 20-1-2013; 401-405
dc.identifier1567-1348
dc.identifier1567-1348
dc.descriptionCommunity-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections have become a major concern worldwide. We conducted a prospective multicenter study of invasive CA-MRSA to evaluate clinical features and genotype of strains causing invasive infections in Argentina. A total of 55 patients with invasive CA-MRSA infections were included. Most patients (60%) had bloodstream infections, 42% required admission to intensive care unit and 16% died. No CA-MRSA isolates were multiresistant (resistant ≥ 3 classes of antibiotics). All isolates carried Panton-Valentine leukocidin (PVL) genes and staphylococcal cassette chromosome (SCCmec) type IV. The majority CA-MRSA strains belonged to ST30 and had identical PFGE patterns, qualifying as a clonal dissemination of a highly transmissible strain. In patients with invasive infections this clone genotyped as pulsed-field gel electrophoresis type C- ST30, SCCmec type IVc-spa type 019, PVL positive has become predominant and replaced the previously described CA-MRSA clone (PFGE type A, ST5, SCCmec type IV, spa type 311).
dc.descriptionCommunity-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections have become a major concern worldwide. We conducted a prospective multicenter study of invasive CA-MRSA to evaluate clinical features and genotype of strains causing invasive infections in Argentina. A total of 55 patients with invasive CA-MRSA infections were included. Most patients (60%) had bloodstream infections, 42% required admission to intensive care unit and 16% died. No CA-MRSA isolates were multiresistant (resistant ≥ 3 classes of antibiotics). All isolates carried Panton-Valentine leukocidin (PVL) genes and staphylococcal cassette chromosome (SCCmec) type IV. The majority CA-MRSA strains belonged to ST30 and had identical PFGE patterns, qualifying as a clonal dissemination of a highly transmissible strain. In patients with invasive infections this clone genotyped as pulsed-field gel electrophoresis type C- ST30, SCCmec type IVc-spa type 019, PVL positive has become predominant and replaced the previously described CA-MRSA clone (PFGE type A, ST5, SCCmec type IV, spa type 311).
dc.descriptionFil: Fernandez, Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina
dc.descriptionFil: Fernandez, Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina
dc.descriptionFil: de Vedia, Luis Alberto. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas F. J. Muñiz; Argentina
dc.descriptionFil: de Vedia, Luis Alberto. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas F. J. Muñiz; Argentina
dc.descriptionFil: Lopez Furst, M, J.. Sanatorio Mendez; Argentina
dc.descriptionFil: Lopez Furst, M, J.. Sanatorio Mendez; Argentina
dc.descriptionFil: Gardella, Noella Mariel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina
dc.descriptionFil: Gardella, Noella Mariel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina
dc.descriptionFil: Di Gregorio, Sabrina Noelia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina
dc.descriptionFil: Di Gregorio, Sabrina Noelia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina
dc.descriptionFil: Ganaha, M. C.. Hospital Vicente López y Planes; Argentina
dc.descriptionFil: Ganaha, M. C.. Hospital Vicente López y Planes; Argentina
dc.descriptionFil: Prieto, S.. Hospital Nuestra Señora de Luján; Argentina
dc.descriptionFil: Prieto, S.. Hospital Nuestra Señora de Luján; Argentina
dc.descriptionFil: Carbone, E.. Hospital Aeronáutico; Argentina
dc.descriptionFil: Carbone, E.. Hospital Aeronáutico; Argentina
dc.descriptionFil: Lista, N.. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas F. J. Muñiz; Argentina
dc.descriptionFil: Lista, N.. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas F. J. Muñiz; Argentina
dc.descriptionFil: Rotrying, F.. Universidad Abierta Interamericana. Hospital Escuela; Argentina
dc.descriptionFil: Rotrying, F.. Universidad Abierta Interamericana. Hospital Escuela; Argentina
dc.descriptionFil: Stryjewski, M. D.. Centro de Educaciones Médicas e Investigación Clínica;
dc.descriptionFil: Stryjewski, M. D.. Centro de Educaciones Médicas e Investigación Clínica;
dc.descriptionFil: Mollerach, Marta Eugenia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina
dc.descriptionFil: Mollerach, Marta Eugenia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.languageeng
dc.publisherElsevier
dc.publisherElsevier
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.meegid.2012.12.018
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.meegid.2012.12.018
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1567134813000038
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1567134813000038
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subjectMethicillin-Resistance Community-Associated Staphylococcus Aureus
dc.subjectMethicillin-Resistance Community-Associated Staphylococcus Aureus
dc.subjectMrsa Invasive Infection
dc.subjectMrsa Invasive Infection
dc.subjectMolecular Epidemiology
dc.subjectMolecular Epidemiology
dc.subjecthttps://purl.org/becyt/ford/3.3
dc.subjecthttps://purl.org/becyt/ford/3.3
dc.subjecthttps://purl.org/becyt/ford/3
dc.subjecthttps://purl.org/becyt/ford/3
dc.subjecthttps://purl.org/becyt/ford/3.3
dc.subjecthttps://purl.org/becyt/ford/3.3
dc.subjecthttps://purl.org/becyt/ford/3
dc.subjecthttps://purl.org/becyt/ford/3
dc.titleMethicillin-resistant Staphylococcus aureus ST30-SCCmec IVc clone as the major cause of community-acquired invasive infections in Argentina
dc.titleMethicillin-resistant Staphylococcus aureus ST30-SCCmec IVc clone as the major cause of community-acquired invasive infections in Argentina
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


Este ítem pertenece a la siguiente institución