Epigenetics in Alternative Pre-mRNA Splicing

dc.creatorLuco, Reini F.
dc.creatorAlló, Mariano
dc.creatorSchor, Ignacio Esteban
dc.creatorKornblihtt, Alberto Rodolfo
dc.creatorMisteli, Tom
dc.date.accessioned2017-07-13T18:31:24Z
dc.date.available2017-07-13T18:31:24Z
dc.date.created2017-07-13T18:31:24Z
dc.date.issued2011-01
dc.identifierLuco, Reini F.; Alló, Mariano; Schor, Ignacio Esteban; Kornblihtt, Alberto Rodolfo; Misteli, Tom; Epigenetics in Alternative Pre-mRNA Splicing; Cell Press; Cell; 144; 1; 1-2011; 16-26
dc.identifier0092-8674
dc.identifierhttp://hdl.handle.net/11336/20368
dc.identifierCONICET Digital
dc.identifierCONICET
dc.description.abstractAlternative splicing plays critical roles in differentiation, development, and disease and is a major source for protein diversity in higher eukaryotes. Analysis of alternative splicing regulation has traditionally focused on RNA sequence elements and their associated splicing factors, but recent provocative studies point to a key function of chromatin structure and histone modifications in alternative splicing regulation. These insights suggest that epigenetic regulation determines not only what parts of the genome are expressed but also how they are spliced.
dc.languageeng
dc.publisherCell Press
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.cell.2010.11.056
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0092867410013784
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038581/
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEpigenética
dc.subjectSplicing
dc.titleEpigenetics in Alternative Pre-mRNA Splicing
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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