dc.creatorTeixeira, Manoel Jacobsen
dc.creatorPaz, Matheus Gomes da S da
dc.creatorBina, Mauro Tupiniquim
dc.creatorSantos, Scheila Nogueira
dc.creatorRaicher, Irina
dc.creatorGalhardoni, Ricardo
dc.creatorFernandes, Diego Toledo
dc.creatorYeng, Lin T
dc.creatorBaptista, Abrahão F
dc.creatorAndrade, Daniel Ciampi de
dc.date.accessioned2015-05-12T18:01:14Z
dc.date.accessioned2018-07-04T17:05:09Z
dc.date.available2015-05-12T18:01:14Z
dc.date.available2018-07-04T17:05:09Z
dc.date.created2015-05-12T18:01:14Z
dc.date.issued2015
dc.identifierBMC Neurology. 2015 May 04;15(1):73
dc.identifierhttp://dx.doi.org/10.1186/s12883-015-0329-x
dc.identifierhttp://www.producao.usp.br/handle/BDPI/48852
dc.identifier10.1186/s12883-015-0329-x
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1644446
dc.description.abstractAbstract Review The pain that commonly occurs after brachial plexus avulsion poses an additional burden on the quality of life of patients already impaired by motor, sensory and autonomic deficits. Evidence-based treatments for the pain associated with brachial plexus avulsion are scarce, thus frequently leaving the condition refractory to treatment with the standard methods used to manage neuropathic pain. Unfortunately, little is known about the pathophysiology of brachial plexus avulsion. Available evidence indicates that besides primary nerve root injury, central lesions related to the abrupt disconnection of nerve roots from the spinal cord may play an important role in the genesis of neuropathic pain in these patients and may explain in part its refractoriness to treatment. Conclusions The understanding of both central and peripheral mechanisms that contribute to the development of pain is of major importance in order to propose more effective treatments for brachial plexus avulsion-related pain. This review focuses on the current understanding about the occurrence of neuropathic pain in these patients and the role played by peripheral and central mechanisms that provides insights into its treatment. Summary Pain after brachial plexus avulsion involves both peripheral and central components; thereby it is characterized as a mixed (central and peripheral) neuropathic pain syndrome.
dc.languageen
dc.publisherBioMed Central
dc.relationBMC Neurology
dc.rightsTeixeira et al.; licensee BioMed Central.
dc.rightsopenAccess
dc.subjectPlexus avulsion
dc.subjectNeuropathic pain
dc.subjectChronic pain
dc.subjectTrauma
dc.subjectBrachial plexus
dc.titleNeuropathic pain after brachial plexus avulsion - central and peripheral mechanisms
dc.typeArtículos de revistas


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