Convergence of two major pathophysiologic mechanisms in nasal polyposis: immune response to Staphylococcus aureus and airway remodeling

dc.creatorPezato, Rogério
dc.creatorBalsalobre, Leonardo
dc.creatorLima, Milena
dc.creatorBezerra, Thiago F P
dc.creatorVoegels, Richard L
dc.creatorGregório, Luis C
dc.creatorStamm, Aldo C
dc.creatorZele, Thibaut v
dc.date.accessioned2015-01-09T17:24:10Z
dc.date.accessioned2018-07-04T16:59:36Z
dc.date.available2015-01-09T17:24:10Z
dc.date.available2018-07-04T16:59:36Z
dc.date.created2015-01-09T17:24:10Z
dc.date.issued2013-03-28
dc.identifierJournal of Otolaryngology - Head & Neck Surgery. 2013 Mar 28;42(1):27
dc.identifierhttp://dx.doi.org/10.1186/1916-0216-42-27
dc.identifierhttp://www.producao.usp.br/handle/BDPI/47523
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1643188
dc.description.abstractAbstract This review is addressed two pathophysiologic mechanisms implicated in the pathogenesis of nasal polyposis: the unique remodeling process found in nasal polyp tissue and the immune response of patients with nasal polyposis to Staphylococcus aureus. These two theories converge to the same direction in different aspects, including decreased extracellular matrix production, impaired T regulation and favoring of a Th2 immune response. In patients with nasal polyposis, an exaggerated immune response to Staphylococcus aureus may aggravate the airway remodeling process.
dc.languageen
dc.rightsPezato et al.; licensee BioMed Central Ltd.
dc.titleConvergence of two major pathophysiologic mechanisms in nasal polyposis: immune response to Staphylococcus aureus and airway remodeling
dc.typeArtículos de revistas


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