Pancreatite crônica em caprinos: primeiro relato de caso na América do Sul

Abstract

This study reports the clinical and laboratory profile of an adult Saanen goat with chronic pancreatitis admitted in the Cattle and Small Ruminant Practice. The main complaint was loss of weight in the absence of dysphagia and anorexia. Physical examination showed normal vital function, cachexia, body condition score equal (ECC) to 2 (1 to 5), and polyphagia. Parasitological examination of feces and radial immunodiffusion for caprine arthritis encephalitis presented negative results. Laboratory exams showed fasting hyperglycemia, glucosuria, ketonuria and aciduria. Serum amylase activity was 10.5U/L, lower than the values obtained from two healthy animals kept in the CBPR (21.2U/L and 52.2U/L), once reference values for amylase in goats are not available. Insulin assessment, however, was not carried out because there are no laboratories in Brazil that work with goat insulin. After two episodes of bronchopneumonia, the animal was euthanized and necropsied. Hystopathological examination of the pancreas showed serious chronic-active pancreatitis, with marked acinar fibrosis and atrophy associated to rarefaction of islets of Langerhans. Besides, there were ductal hyperplasia with irregularities, and mucoid metaplasia. Thus, clinical, laboratorial and histopathological findings indicate that the animal presented primary chronic pancreatitis, compromising the endocrine and exocrine pancreas.