Grandisin caused morphological changes larval and toxicity on Aedes aegypti

dc.creatorLeite, Ana Carolina C. F.
dc.creatorKato, Massuo Jorge
dc.creatorSoares, Renata O. A.
dc.creatorGuimarães, Anthony E.
dc.creatorSantos-Mallet, Jacenir R.
dc.creatorCabral, Marise M. O.
dc.date.accessioned2013-11-04T12:24:34Z
dc.date.accessioned2018-07-04T16:34:31Z
dc.date.available2013-11-04T12:24:34Z
dc.date.available2018-07-04T16:34:31Z
dc.date.created2013-11-04T12:24:34Z
dc.date.issued2012
dc.identifierRev. bras. farmacogn.,v.22,n.3,p.517-521,2012
dc.identifier0102-695X
dc.identifierhttp://www.producao.usp.br/handle/BDPI/38996
dc.identifier10.1590/S0102-695X2012005000016
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000300008&lng=en&nrm=iso&tlng=en
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_abstract&pid=S0102-695X2012000300008&lng=en&nrm=iso&tlng=en
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_pdf&pid=S0102-695X2012000300008&lng=en&nrm=iso&tlng=en
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1637453
dc.description.abstractDengue is a tropical disease caused by an arbovirus transmitted by Aedes aegypti. Since no effective vaccine is available for treating dengue, the present study focused on population vector control through investigating the use of the lignan grandisin, isolated from Piper solmsianum C. DC., Piperaceae, against the larvae of A. aegypti. Grandisin caused larval (L3) mortality at LC50 150 µg/mL. Histological analysis on A. aegypti larvae treated with grandisin (LC50 50 µg/mL) showed changes in the anterior-middle midgut, with intense tissue destruction and cell disorganization.
dc.languageeng
dc.publisherSociedade Brasileira de Farmacognosia
dc.relationRevista Brasileira de Farmacognosia
dc.rightsopenAccess
dc.subjectAedes aegypti
dc.subjectPiper solmsianum
dc.subjecthistology
dc.subjecttoxicity
dc.subjecttropical disease
dc.titleGrandisin caused morphological changes larval and toxicity on Aedes aegypti
dc.typeArtículos de revistas


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