Analysis of phase transition and dehydration processes of nevirapine

dc.creatorOliveira, George G. G. de
dc.creatorFerraz, Humberto Gomes
dc.creatorSeverino, Patricia
dc.creatorSouto, Eliana B.
dc.date.accessioned2013-11-05T10:53:26Z
dc.date.accessioned2018-07-04T16:15:52Z
dc.date.available2013-11-05T10:53:26Z
dc.date.available2018-07-04T16:15:52Z
dc.date.created2013-11-05T10:53:26Z
dc.date.issued2012
dc.identifierJOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, DORDRECHT, v. 108, n. 1, p. 53-57, APR, 2012
dc.identifier1388-6150
dc.identifierhttp://www.producao.usp.br/handle/BDPI/41075
dc.identifier10.1007/s10973-011-1424-x
dc.identifierhttp://dx.doi.org/10.1007/s10973-011-1424-x
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1633590
dc.description.abstractSolid-state characterization of crystalline drugs is an important pre-formulation step for the development and design of solid dosage forms, such as pellets and tablets. In this study, phase transition and dehydration processes of nevirapine have been studied by differential scanning calorimetry and thermogravimetry differential thermal analysis to overcome the problems of drug formulation, namely poor solubility and poor content uniformity. Phase solubility studies elucidated the mechanism of enhanced nevirapine solubility.
dc.languageeng
dc.publisherSPRINGER
dc.publisherDORDRECHT
dc.relationJOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
dc.rightsCopyright SPRINGER
dc.rightsclosedAccess
dc.subjectNEVIRAPINE
dc.subjectDIFFERENTIAL SCANNING CALORIMETRY (DSC)
dc.subjectTHERMOGRAVIMETRY DIFFERENTIAL THERMAL ANALYSIS (TG-DTA)
dc.subjectSOLID DOSAGE FORMS
dc.titleAnalysis of phase transition and dehydration processes of nevirapine
dc.typeArtículos de revistas


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