dc.creatorFernandes, João Paulo dos Santos
dc.creatorMoura, Anna Carolina Volpi Mello de
dc.creatorMarques, Marcia Martins
dc.creatorNicoletti, Maria Aparecida
dc.date.accessioned2013-10-29T12:31:01Z
dc.date.accessioned2018-07-04T16:06:50Z
dc.date.available2013-10-29T12:31:01Z
dc.date.available2018-07-04T16:06:50Z
dc.date.created2013-10-29T12:31:01Z
dc.date.issued2013-08-02
dc.identifierACTA ODONTOLOGICA SCANDINAVICA, LONDON, v. 70, n. 6, supl. 1, Part 3, pp. 610-614, DEC, 2012
dc.identifier0001-6357
dc.identifierhttp://www.producao.usp.br/handle/BDPI/36226
dc.identifier10.3109/00016357.2011.645060
dc.identifierhttp://dx.doi.org/10.3109/00016357.2011.645060
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1631591
dc.description.abstractObjective. This in vitro study evaluated the cytotoxic effects of the Curcuma zedoaria (Christm.) Roscoe (popular name: zedoary) fluid extract, as used in preparations for oral hygiene, mostly for anti-septic purposes. Materials and methods. The cell viability and cell growth were assessed by Trypan blue dye exclusion assay using the LMF cell line derived from oral mucosa. Cell viability (short-term assay) was measured 0, 6, 12 and 24 h after contact with the fluid extract. Cell growth (long-term assay) was analyzed in 1, 3, 5 and 7 days. The experimental groups were those testing the fluid extract obtained from the zedoary rhizome and the extractor liquid (ethanol 70 degrees GL) in the concentrations of 0.01-0.0001% v/v. Fresh DMEM were used in the control cultures. Results. Short-term assay-all studied cultures maintained stable cell viability; Long-term assay-there was progressive cell growth in all studied cultures. Conclusion. According to the results, the zedoary fluid extract presents low cytotoxicity and probably can be used in the oral hygiene products.
dc.languageeng
dc.publisherINFORMA HEALTHCARE
dc.publisherLONDON
dc.relationACTA ODONTOLOGICA SCANDINAVICA
dc.rightsCopyright INFORMA HEALTHCARE
dc.rightsrestrictedAccess
dc.subjectCELL CULTURE
dc.subjectCYTOTOXICITY
dc.subjectZEDOARY
dc.subjectVEGETAL EXTRACT
dc.titleCytotoxicity evaluation of Curcuma zedoaria (Christm.) Roscoe fluid extract used in oral hygiene products
dc.typeArtículos de revistas


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