dc.creator | Beldi, Mariana Carmezim | |
dc.creator | Tacla, Maricy | |
dc.creator | Caiaffa-Filho, Helio | |
dc.creator | Ab'saber, Alexandre | |
dc.creator | Siqueira, Sheila | |
dc.creator | Baracat, Edmund Chada | |
dc.creator | Ferreira Alves, Venancio Avancini | |
dc.creator | Longatto-Filho, Adhemar | |
dc.date.accessioned | 2013-08-16T18:48:15Z | |
dc.date.accessioned | 2018-07-04T15:54:49Z | |
dc.date.available | 2013-08-16T18:48:15Z | |
dc.date.available | 2018-07-04T15:54:49Z | |
dc.date.created | 2013-08-16T18:48:15Z | |
dc.date.issued | 2012 | |
dc.identifier | ACTA CYTOLOGICA, BASEL, v. 56, n. 2, supl. 1, Part 3, pp. 160-165, DEC, 2012 | |
dc.identifier | 0001-5547 | |
dc.identifier | http://www.producao.usp.br/handle/BDPI/32604 | |
dc.identifier | 10.1159/000335145 | |
dc.identifier | http://dx.doi.org/10.1159/000335145 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1629121 | |
dc.description.abstract | Objectives: Robust evidence now supports human papillomavirus (HPV) testing as a more effective option to screening and as more sensitive than cytology in detecting high-grade cervical intraepithelial neoplasia. Our goal was to analyze the performance of the Hybrid Capture II (HC2) assay for high-risk HPV (hrHPV) in women undergoing gynecological examination at a public health hospital as part of the evaluation of HPV screening as an alternative or complement to cytology. Study Design: This analysis is a subset of a cross-sectional study carried out at a large public hospital serving a predominantly low-resource population. A total of 705 women were enrolled; the sensitivity and specificity of each test were estimated and compared. Results: The analysis identified 272 hrHPV-positive women (mean age 36.3 years) and 433 hrHPV-negative women (mean age 41.2 years). HPV testing showed a significantly increased sensitivity of the HC2 assay versus cytology (84.5 vs. 69.7%; p < 0.0001) but a lower specificity (49.90 vs. 88.78%; p < 0.0001). Conclusion: The combination of both methods seems to be useful in improving detection of cervical lesions. Copyright (C) 2012 S. Karger AG, Basel | |
dc.language | eng | |
dc.publisher | KARGER | |
dc.publisher | BASEL | |
dc.relation | ACTA CYTOLOGICA | |
dc.rights | Copyright KARGER | |
dc.rights | restrictedAccess | |
dc.subject | CYTOLOGY | |
dc.subject | PAP TEST | |
dc.subject | HUMAN PAPILLOMAVIRUS TESTING | |
dc.subject | PRIMARY SCREENING | |
dc.title | Implementing Human Papillomavirus Testing in a Public Health Hospital: Challenges and Opportunities | |
dc.type | Artículos de revistas | |