dc.creator | ROCHA, Lenilson C. | |
dc.creator | FERREIRA, Hercules V. | |
dc.creator | PIMENTA, Eli F. | |
dc.creator | BERLINCK, Roberto G. S. | |
dc.creator | SELEGHIM, Mirna H. R. | |
dc.creator | JAVAROTI, Darci C. D. | |
dc.creator | SETTE, Lara D. | |
dc.creator | BONUGLI, Rafaella C. | |
dc.creator | PORTO, Andre L. M. | |
dc.date.accessioned | 2012-10-20T05:30:54Z | |
dc.date.accessioned | 2018-07-04T15:51:28Z | |
dc.date.available | 2012-10-20T05:30:54Z | |
dc.date.available | 2018-07-04T15:51:28Z | |
dc.date.created | 2012-10-20T05:30:54Z | |
dc.date.issued | 2009 | |
dc.identifier | BIOTECHNOLOGY LETTERS, v.31, n.10, p.1559-1563, 2009 | |
dc.identifier | 0141-5492 | |
dc.identifier | http://producao.usp.br/handle/BDPI/31715 | |
dc.identifier | 10.1007/s10529-009-0037-y | |
dc.identifier | http://dx.doi.org/10.1007/s10529-009-0037-y | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1628353 | |
dc.description.abstract | The asymmetric reduction of 2-chloro-1-phenylethanone (1) by seven strains of marine fungi was evaluated and afforded (S)-(-)-2-chloro-1-phenylethanol with, in the best case, an enantiomeric excess of 50% and an isolated yield of 60%. The ability of marine fungi to catalyse the reduction was directly dependent on growth in artificial sea water-based medium containing a high concentration of Cl(-) (1.2 M). When fungi were grown in the absence of artificial sea water, no reduction of 1 by whole cells was observed. The biocatalytic reduction of 1 was more efficient at neutral rather than acidic pH values and in the absence of glucose as co-substrate. | |
dc.language | eng | |
dc.publisher | SPRINGER | |
dc.relation | Biotechnology Letters | |
dc.rights | Copyright SPRINGER | |
dc.rights | restrictedAccess | |
dc.subject | Biocatalysis | |
dc.subject | Bioreduction | |
dc.subject | Chlorohydrin | |
dc.subject | Marine fungi | |
dc.title | Bioreduction of alpha-chloroacetophenone by whole cells of marine fungi | |
dc.type | Artículos de revistas | |