An Improved Procedure for the Preparation of [Bis(2,2,2-trifluoroethyl)phosphono]acetic Acid

dc.creatorPRADO, Viviana da Silva
dc.creatorBURTOLOSO, Antonio Carlos B.
dc.date.accessioned2012-10-20T05:30:49Z
dc.date.accessioned2018-07-04T15:51:25Z
dc.date.available2012-10-20T05:30:49Z
dc.date.available2018-07-04T15:51:25Z
dc.date.created2012-10-20T05:30:49Z
dc.date.issued2010
dc.identifierSYNTHESIS-STUTTGART, n.2, p.361-363, 2010
dc.identifier0039-7881
dc.identifierhttp://producao.usp.br/handle/BDPI/31702
dc.identifier10.1055/s-0029-1217086
dc.identifierhttp://dx.doi.org/10.1055/s-0029-1217086
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1628340
dc.description.abstractA different and improved procedure for the preparation of [bis(2,2,2-trifluoroethyl)phosphono]acetic acid in just one step from bis(2,2,2-trifluoroethyl)phosphonate is described. The protocol employs a Michaelis-Becker reaction between commercially available bis(2,2,2-trifluoroethyl) phosphonate and bromoacetic acid, furnishing [bis(2,2,2-trifluoroethyl)phosphono]acetic acid in 50-54% yield.
dc.languageeng
dc.publisherGEORG THIEME VERLAG KG
dc.relationSynthesis-stuttgart
dc.rightsCopyright GEORG THIEME VERLAG KG
dc.rightsrestrictedAccess
dc.subject[bis(2,2,2-trifluoroethyl)phosphono]acetic acid
dc.subjectHorner-Wadsworth-Emmons (HWE) reaction
dc.subjectMichaelis-Becker reaction
dc.subjectStill-Gennari reagents
dc.titleAn Improved Procedure for the Preparation of [Bis(2,2,2-trifluoroethyl)phosphono]acetic Acid
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución