dc.creator | BARRETO, Wagner J. | |
dc.creator | BARRETO, Sonia R. G. | |
dc.creator | ANDO, Romulo A. | |
dc.creator | SANTOS, Paulo S. | |
dc.creator | DIMAURO, Eduardo | |
dc.creator | JORGE, Thiago | |
dc.date.accessioned | 2012-10-20T05:23:36Z | |
dc.date.accessioned | 2018-07-04T15:49:26Z | |
dc.date.available | 2012-10-20T05:23:36Z | |
dc.date.available | 2018-07-04T15:49:26Z | |
dc.date.created | 2012-10-20T05:23:36Z | |
dc.date.issued | 2008 | |
dc.identifier | SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, v.71, n.4, p.1419-1424, 2008 | |
dc.identifier | 1386-1425 | |
dc.identifier | http://producao.usp.br/handle/BDPI/31248 | |
dc.identifier | 10.1016/j.saa.2008.04.014 | |
dc.identifier | http://dx.doi.org/10.1016/j.saa.2008.04.014 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1627886 | |
dc.description.abstract | The anionic complexes [Cu(L(1-))(3)](1-), L(-) = dopasemiquinone or L-dopasemiqui none, were prepared and characterized. The complexes are stable in aqueous solution showing intense absorption bands at ca. 605 nm for Cu(II)-L-dopasemiquinone and at ca. 595 nm for Cu(II)-dopasemiquinone in the UV-vis spectra, that can be assigned to intraligand transitions. Noradrenaline and adrenaline, under the same reaction conditions, did not yield Cu-complexes, despite the bands in the UV region showing that noradrenaline and adrenaline were oxidized during the process. The complexes display a resonance Raman effect, and the most enhanced bands involve ring modes and particularly the vCC + vCO stretching mode at ca. 1384 cm(-1). The free radical nature of the ligands and the oxidation state of the Cu(II) were confirmed by the EPR spectra that display absorptions assigned to organic radicals with g= 2.0005 and g = 2.0923, and for Cu(II) with g = 2.008 and g = 2.0897 for L-dopasemiquinone and dopasemiquinone, respectively. The possibility that dopamine and L-dopa can form stable and aqueous-soluble copper complexes at neutral pH, whereas noradrenaline and adrenaline cannot, may be important in understanding how Cu(II)-dopamine crosses the cellular membrane as proposed in the literature to explain the role of copper in Wilson disease. (c) 2008 Elsevier B.V. All rights reserved. | |
dc.language | eng | |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | |
dc.relation | Spectrochimica Acta Part A-molecular and Biomolecular Spectroscopy | |
dc.rights | Copyright PERGAMON-ELSEVIER SCIENCE LTD | |
dc.rights | restrictedAccess | |
dc.subject | Resonance Raman | |
dc.subject | Dioxolene | |
dc.subject | Metal complex | |
dc.subject | Catecholate | |
dc.subject | Semiquinone | |
dc.subject | Wilson disease | |
dc.title | Raman, IR, UV-vis and EPR characterization of two copper dioxolene complexes derived from L-dopa and dopamine | |
dc.type | Artículos de revistas | |