Estimation of the mean quality-adjusted survival using a multistate model for the sojourn times

dc.creatorTUNES-DA-SILVA, Gisela
dc.creatorSEN, Pranab K.
dc.creatorPEDROSO-DE-LIMA, Antonio Carlos
dc.date.accessioned2012-10-20T04:44:51Z
dc.date.accessioned2018-07-04T15:46:24Z
dc.date.available2012-10-20T04:44:51Z
dc.date.available2018-07-04T15:46:24Z
dc.date.created2012-10-20T04:44:51Z
dc.date.issued2008
dc.identifierJOURNAL OF STATISTICAL PLANNING AND INFERENCE, v.138, n.8, p.2267-2282, 2008
dc.identifier0378-3758
dc.identifierhttp://producao.usp.br/handle/BDPI/30528
dc.identifier10.1016/j.jspi.2007.10.010
dc.identifierhttp://dx.doi.org/10.1016/j.jspi.2007.10.010
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1627167
dc.description.abstractIn clinical trials, it may be of interest taking into account physical and emotional well-being in addition to survival when comparing treatments. Quality-adjusted survival time has the advantage of incorporating information about both survival time and quality-of-life. In this paper, we discuss the estimation of the expected value of the quality-adjusted survival, based on multistate models for the sojourn times in health states. Semiparametric and parametric (with exponential distribution) approaches are considered. A simulation study is presented to evaluate the performance of the proposed estimator and the jackknife resampling method is used to compute bias and variance of the estimator. (C) 2007 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherELSEVIER SCIENCE BV
dc.relationJournal of Statistical Planning and Inference
dc.rightsCopyright ELSEVIER SCIENCE BV
dc.rightsrestrictedAccess
dc.subjectquality-of-life
dc.subjectsurvival analysis
dc.subjectmultistate models
dc.subjectexponential distribution
dc.subjectsemiparametric proportional hazards
dc.titleEstimation of the mean quality-adjusted survival using a multistate model for the sojourn times
dc.typeArtículos de revistas


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