Artículos de revistas
Analytical quantification of low-density lipoprotein using europium tetracycline indicator
Fecha
2009Registro en:
LUMINESCENCE, v.24, n.3, p.189-193, 2009
1522-7235
10.1002/bio.1094
Autor
SILVA, Flavia Rodrigues De Oliveira
Monteiro, Andrea Moreira
Figueiredo Neto, Antonio Martins
Gidlund, Magnus Ake
Vieira Junior, Nilson Dias
COURROL, Lilia Coronato
Institución
Resumen
Low-density lipoprotein (LDL) is known as `bad` cholesterol. If too much LDL circulates in the blood it can be retained in the walls of the arteries, causing atherosclerosis. In this paper we showed an alternative method to quantify LDL using the europium tetracycline (EuTc) indicator. The optical properties of the EuTc complex were investigated in aqueous solutions containing LDL. An enhancement was observed of the europium luminescence in the solutions with LDL compared those without the lipoprotein. A method to quantify the amount of LDL in a sample, based on EuTc enhanced luminescence, is proposed. The enhancement mechanism is also discussed. Copyright (C) 2009 John Wiley & Sons, Ltd.