dc.creatorBARRETO-CHAVES, Maria Luiza
dc.creatorMONTEIRO, Priscilla de Souza
dc.creatorFUERSTENAU, Cristina R.
dc.date.accessioned2012-10-20T03:16:15Z
dc.date.accessioned2018-07-04T15:33:48Z
dc.date.available2012-10-20T03:16:15Z
dc.date.available2018-07-04T15:33:48Z
dc.date.created2012-10-20T03:16:15Z
dc.date.issued2011
dc.identifierCURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY, v.18, n.5, p.300-303, 2011
dc.identifier1752-296X
dc.identifierhttp://producao.usp.br/handle/BDPI/27837
dc.identifier10.1097/MED.0b013e32834a785c
dc.identifierhttp://dx.doi.org/10.1097/MED.0b013e32834a785c
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1624481
dc.description.abstractPurpose of review Description of the progress about the vascular effects promoted by thyroid hormones. Recent findings Over the past few years, a number of studies have shown that in addition to genomic effects on blood vessels, thyroid hormones exert extranuclear nongenomic effects on vascular smooth muscle cells and endothelium. These nongenomic effects occur rapidly and do not involve thyroid hormone response elements-mediated transcriptional events. In this context, the genomic and nongenomic events promoted by thyroid hormones act in concert to control the vascular hemodynamic and regulate the cardiovascular function. Summary Considering the antiatherogenic property of thyroid hormones and the rapid effects produced by this molecule as a vasodilator, including that in the coronary bed, a better understanding of the molecular mechanisms involved in its action may contribute to the development of drugs that can be clinically used to increase the known benefits promoted by thyroid hormones in cardiovascular physiology.
dc.languageeng
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.relationCurrent Opinion in Endocrinology Diabetes and Obesity
dc.rightsCopyright LIPPINCOTT WILLIAMS & WILKINS
dc.rightsrestrictedAccess
dc.subjectendothelium
dc.subjectsystemic vascular resistance
dc.subjectthyroid hormones
dc.subjectvascular smooth muscle cells
dc.titleAcute actions of thyroid hormone on blood vessel biochemistry and physiology
dc.typeArtículos de revistas


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