dc.creatorRONDO, Patricia Helen Carvalho
dc.creatorCONDE, Andreia
dc.creatorSOUZA, Miriam Coelho
dc.creatorSAKUMA, Alice
dc.date.accessioned2012-10-20T01:31:02Z
dc.date.accessioned2018-07-04T15:27:48Z
dc.date.available2012-10-20T01:31:02Z
dc.date.available2018-07-04T15:27:48Z
dc.date.created2012-10-20T01:31:02Z
dc.date.issued2011
dc.identifierTRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, v.105, n.9, p.525-530, 2011
dc.identifier0035-9203
dc.identifierhttp://producao.usp.br/handle/BDPI/26589
dc.identifier10.1016/j.trstmh.2011.05.012
dc.identifierhttp://dx.doi.org/10.1016/j.trstmh.2011.05.012
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1623251
dc.description.abstractThis study investigated the relationship between iron deficiency/iron deficiency anaemia, assessed by several parameters, and blood lead concentration in children. This cross-sectional study involved 384 Brazilian children, aged 2-11 years, who lived near a lead-manipulating industry. Complete blood counts were obtained by an automated cell counter. Serum iron, total iron binding capacity (TIBC) and ferritin were determined respectively, by colorimetric, turbidimetric methods and chemiluminescence. Blood lead was measured by atomic absorption spectrophotometry. The impact of several parameters for assessment of iron status (haemoglobin, serum iron, TIBC, transferrin saturation, ferritin, red cell indices and red cell distribution width) and variables (gender, age, mother`s education, income, body mass index, iron intake, and distance from home to lead-manipulating industry) on blood lead concentration was determined by multiple linear regression. There were significant negative associations between blood lead and the distance from home to the lead-manipulating industry (P < 0.001), Hb (P = 0.019), and ferritin (P=0.023) (R(2)=0.14). Based on these results, further epidemiological studies are necessary to investigate the impact of interventions like iron supplementation or fortification, as an attempt to decrease blood lead in children. (C) 2011 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
dc.languageeng
dc.publisherELSEVIER SCIENCE INC
dc.relationTransactions of the Royal Society of Tropical Medicine and Hygiene
dc.rightsCopyright ELSEVIER SCIENCE INC
dc.rightsrestrictedAccess
dc.subjectLead toxicity
dc.subjectBlood lead
dc.subjectIron deficiency
dc.subjectIron deficiency anaemia
dc.subjectChildren
dc.titleIron deficiency anaemia and blood lead concentrations in Brazilian children
dc.typeArtículos de revistas


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