dc.creatorTRAVER, Luis Angelo Marti
dc.creatorMARTINEZ, Francisco Eulogio
dc.creatorFERRIOLLI, Eduardo
dc.creatorMARCHINI, Julio Sergio
dc.creatorMONTEIRO, Jacqueline Pontes
dc.creatorPFRIMER, Karina
dc.creatorSANCHEZ, Ana Paula Michelin
dc.creatorOLIVEIRA, Thais de
dc.creatorDUCATTI, Carlos
dc.creatorCAMELO JR., Jose Simon
dc.date.accessioned2012-10-19T23:33:33Z
dc.date.accessioned2018-07-04T15:19:19Z
dc.date.available2012-10-19T23:33:33Z
dc.date.available2018-07-04T15:19:19Z
dc.date.created2012-10-19T23:33:33Z
dc.date.issued2009
dc.identifierJOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, v.48, n.4, p.471-474, 2009
dc.identifier0277-2116
dc.identifierhttp://producao.usp.br/handle/BDPI/24825
dc.identifierhttp://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000264671600015&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1621551
dc.description.abstractThere is an increasing interest about the use of stable isotopes for body composition analysis in pediatrics. To ensure the success of total body water analysis by the deuterium dilution method, it is fundamental to determine the equilibrium tune (plateau) of deuterium in the body fluid studied. Objectives: We report here the equilibration time of deuterium oxide in the saliva of newborns after oral intake of the isotope. Methods: Twenty healthy term newborn infants, 10 males and 10 females, were analyzed. Saliva was collected from each newborn before the oral administration of a 100 mg/kg dose of deuterium oxide (baseline sample) and then at 1-hour intervals for 5 hours after administration. Deuterium enrichment of saliva was determined by isotope ratio mass spectrometry according to the recommendations of the International Atomic Energy Agency. Results: The plateau time of deuterium in saliva occurred 3 hours after oral administration of the stable isotope. Conclusion: These data are essential for further studies on the body composition of newborn infants. To the best of our knowledge, this is the first study regarding the equilibration time of deuterium in the saliva of term newborns. JPGN 48:471-474, 2009.
dc.languageeng
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.relationJournal of Pediatric Gastroenterology and Nutrition
dc.rightsCopyright LIPPINCOTT WILLIAMS & WILKINS
dc.rightsrestrictedAccess
dc.subjectBody composition
dc.subjectDeuterium
dc.subjectNewborn
dc.subjectSaliva
dc.subjectTBW
dc.titleDeuterium Equilibrium Time in Saliva of Newborn Infants
dc.typeArtículos de revistas


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