dc.creatorNASTRI, Carolina O.
dc.creatorFERRIANI, Rui A.
dc.creatorROCHA, Isa A.
dc.creatorMARTINS, Wellington P.
dc.date.accessioned2012-10-19T23:01:03Z
dc.date.accessioned2018-07-04T15:18:02Z
dc.date.available2012-10-19T23:01:03Z
dc.date.available2018-07-04T15:18:02Z
dc.date.created2012-10-19T23:01:03Z
dc.date.issued2010
dc.identifierJOURNAL OF ASSISTED REPRODUCTION AND GENETICS, v.27, n.2/Mar, p.121-128, 2010
dc.identifier1058-0468
dc.identifierhttp://producao.usp.br/handle/BDPI/24530
dc.identifier10.1007/s10815-010-9387-6
dc.identifierhttp://dx.doi.org/10.1007/s10815-010-9387-6
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1621258
dc.description.abstractTo review and discuss the pathophysiology and prevention strategies for ovarian hyperstimulation syndrome (OHSS), which is a condition that may occur in up to 20% of the high risk women submitted to assisted reproductive technology cycles. The English language literature on these topics were reviewed through PubMed and discussed with emphasis on recent data. The role of estradiol, luteinizing hormone, human chorionic gonadotropin (hCG), inflammatory mediators, the renin-angiotensin system and vascular endothelial growth factor is discussed in the pathophysiology of OHSS. In addition we consider the prevention strategies, including coasting, administration of albumin, renin-angiotensin system blockage, dopamine agonist administration, non-steroidal anti-inflammatory administration, GnRH antagonist protocols, reducing hCG dosage, replacement of hCG and in vitro maturation of oocytes (IVM). Among the many prevention strategies that have been discussed, the current evidence points to the replacement of hCG by GnRH agonists in antagonist cycles and the performance of IVM procedures as the safest approaches.
dc.languageeng
dc.publisherSPRINGER/PLENUM PUBLISHERS
dc.relationJournal of Assisted Reproduction and Genetics
dc.rightsCopyright SPRINGER/PLENUM PUBLISHERS
dc.rightsrestrictedAccess
dc.subjectOvarian hyperstimulation syndrome
dc.subjectOvulation induction
dc.subjectAssisted reproductive techniques
dc.titleOvarian hyperstimulation syndrome: pathophysiology and prevention
dc.typeArtículos de revistas


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