Artículos de revistas
Assessing Interethnic Admixture Using an X-Linked Insertion-Deletion Multiplex
Fecha
2009Registro en:
AMERICAN JOURNAL OF HUMAN BIOLOGY, v.21, n.5, p.707-709, 2009
1042-0533
10.1002/ajhb.20950
Autor
RIBEIRO-RODRIGUES, Elzemar Martins
SANTOS, Ney Pereira Carneiro dos
SANTOS, Andrea Kely Campos Ribeiro dos
PEREIRA, Rui
AMORIM, Antonio
GUSMAO, Leonor
ZAGO, Marco Antonio
SANTOS, Sidney Emanuel Batista dos
Institución
Resumen
In this study, a PCR multiplex was optimized, allowing the simultaneous analysis of 13 X-chromosome Insertion/deletion polymorphisms (INDELs). Genetic variation observed in Africans, Europeans, and Native Americans reveals high inter-population variability. The estimated proportions of X-chromosomes in an admixed population from the Brazilian Amazon region show a predominant Amerindian contribution (congruent to 41%), followed by European (congruent to 32%) and African (congruent to 27%) contributions. The proportion of Amerindian contribution based on X-linked data is similar to the expected value based on mtDNA and Y-chromosome information. The accuracy for assessing interethnic admixture, and the high differentiation between African, European, and Native American populations, demonstrates the suitability of this INDEL set to measure ancestry proportions in three-hybrid populations, as it is the case of Latin American populations. Am. J. Hum. Biol. 21:707-709, 2009. (C) 2009 Wiley-Liss, Inc.