dc.creatorALMEIDA, Juliana Roberta da Silva
dc.creatorMACHADO, Fabio Santana
dc.creatorSCHETTINO, Guilherme Paula Pinto
dc.creatorPark, Marcelo
dc.creatorAZEVEDO, Luciano Cesar Pontes
dc.date.accessioned2012-10-19T18:23:37Z
dc.date.accessioned2018-07-04T15:11:09Z
dc.date.available2012-10-19T18:23:37Z
dc.date.available2018-07-04T15:11:09Z
dc.date.created2012-10-19T18:23:37Z
dc.date.issued2010
dc.identifierJOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, v.69, n.2, p.375-382, 2010
dc.identifier0022-5282
dc.identifierhttp://producao.usp.br/handle/BDPI/22990
dc.identifier10.1097/TA.0b013e3181e12b3a
dc.identifierhttp://dx.doi.org/10.1097/TA.0b013e3181e12b3a
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1619721
dc.description.abstractBackground: To evaluate the cardiopulmonary effects of positive end-expiratory pressure (PEEP) equalization to intra-abdominal pressure (IAP) in an experimental model of intra-abdominal hypertension (IAH) and acute lung injury (ALI). Methods: Eight anesthetized pigs were submitted to IAH of 20 mm Hg with a carbon dioxide insufflator for 30 minutes and then submitted to lung lavage with saline and Tween (2.5%). Pressure x volume curves of the respiratory system were performed by a low flow method during IAH and ALI, and PEEP was subsequently adjusted to 27 cm center dot H(2)O for 30 minutes. Results: IAH decreases pulmonary and respiratory system static compliances and increases airway resistance, alveolar-arterial oxygen gradient, and respiratory dead space. The presence of concomitant ALI exacerbates these findings. PEEP identical to AP moderately improved oxygenation and respiratory mechanics; however, an important decline in stroke index and right ventricle ejection fraction was observed. Conclusions: Simultaneous IAH and ALI produce important impairments in the respiratory physiology. PEEP equalization to AP may improve the respiratory performance, nevertheless with a secondary hemodynamic derangement.
dc.languageeng
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.relationJournal of Trauma-injury Infection and Critical Care
dc.rightsCopyright LIPPINCOTT WILLIAMS & WILKINS
dc.rightsrestrictedAccess
dc.subjectAbdominal hypertension
dc.subjectAcute lung injury
dc.subjectPigs
dc.subjectMechanical ventilation
dc.titleCardiopulmonary Effects of Matching Positive End-Expiratory Pressure to Abdominal Pressure in Concomitant Abdominal Hypertension and Acute Lung Injury
dc.typeArtículos de revistas


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