dc.creator | ALMEIDA, Juliana Roberta da Silva | |
dc.creator | MACHADO, Fabio Santana | |
dc.creator | SCHETTINO, Guilherme Paula Pinto | |
dc.creator | Park, Marcelo | |
dc.creator | AZEVEDO, Luciano Cesar Pontes | |
dc.date.accessioned | 2012-10-19T18:23:37Z | |
dc.date.accessioned | 2018-07-04T15:11:09Z | |
dc.date.available | 2012-10-19T18:23:37Z | |
dc.date.available | 2018-07-04T15:11:09Z | |
dc.date.created | 2012-10-19T18:23:37Z | |
dc.date.issued | 2010 | |
dc.identifier | JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, v.69, n.2, p.375-382, 2010 | |
dc.identifier | 0022-5282 | |
dc.identifier | http://producao.usp.br/handle/BDPI/22990 | |
dc.identifier | 10.1097/TA.0b013e3181e12b3a | |
dc.identifier | http://dx.doi.org/10.1097/TA.0b013e3181e12b3a | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1619721 | |
dc.description.abstract | Background: To evaluate the cardiopulmonary effects of positive end-expiratory pressure (PEEP) equalization to intra-abdominal pressure (IAP) in an experimental model of intra-abdominal hypertension (IAH) and acute lung injury (ALI). Methods: Eight anesthetized pigs were submitted to IAH of 20 mm Hg with a carbon dioxide insufflator for 30 minutes and then submitted to lung lavage with saline and Tween (2.5%). Pressure x volume curves of the respiratory system were performed by a low flow method during IAH and ALI, and PEEP was subsequently adjusted to 27 cm center dot H(2)O for 30 minutes. Results: IAH decreases pulmonary and respiratory system static compliances and increases airway resistance, alveolar-arterial oxygen gradient, and respiratory dead space. The presence of concomitant ALI exacerbates these findings. PEEP identical to AP moderately improved oxygenation and respiratory mechanics; however, an important decline in stroke index and right ventricle ejection fraction was observed. Conclusions: Simultaneous IAH and ALI produce important impairments in the respiratory physiology. PEEP equalization to AP may improve the respiratory performance, nevertheless with a secondary hemodynamic derangement. | |
dc.language | eng | |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | |
dc.relation | Journal of Trauma-injury Infection and Critical Care | |
dc.rights | Copyright LIPPINCOTT WILLIAMS & WILKINS | |
dc.rights | restrictedAccess | |
dc.subject | Abdominal hypertension | |
dc.subject | Acute lung injury | |
dc.subject | Pigs | |
dc.subject | Mechanical ventilation | |
dc.title | Cardiopulmonary Effects of Matching Positive End-Expiratory Pressure to Abdominal Pressure in Concomitant Abdominal Hypertension and Acute Lung Injury | |
dc.type | Artículos de revistas | |