dc.creator | MOURA, Carlos Geraldo Guerreiro de | |
dc.creator | MANGUEIRA, Cristovao Luis Pitangueira | |
dc.creator | CRUZ, Luzia Arlinda Sampaio | |
dc.creator | CRUZ, Constanca Margarida Sampaio | |
dc.date.accessioned | 2012-10-19T18:23:02Z | |
dc.date.accessioned | 2018-07-04T15:10:42Z | |
dc.date.available | 2012-10-19T18:23:02Z | |
dc.date.available | 2018-07-04T15:10:42Z | |
dc.date.created | 2012-10-19T18:23:02Z | |
dc.date.issued | 2011 | |
dc.identifier | NEPHRON CLINICAL PRACTICE, v.118, n.4, p.C355-C360, 2011 | |
dc.identifier | 1660-2110 | |
dc.identifier | http://producao.usp.br/handle/BDPI/22890 | |
dc.identifier | 10.1159/000323388 | |
dc.identifier | http://dx.doi.org/10.1159/000323388 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1619621 | |
dc.description.abstract | In a cross-sectional study involving 62 patients with systemic lupus erythematosus (SLE), we found that patients with biopsy-proven lupus nephritis (LN) had higher titers of anti-C1q antibodies than active SLE without nephritis patients. Anti-C1q was associated with a negative predictive value of 94.59%, a positive predictive value of 52%, a sensitivity of 86.66% and a specificity of 74.47% for the diagnosis of LN. We conclude that high titers of anti-C1q antibodies are strongly associated with the presence of active LN, and the negative predictive value of this test for diagnosing LN is very high; therefore, it can influence therapeutic decisions and reduce the number of renal biopsies in patients with SLE. Copyright (C) 2011 S. Karger AG, Basel | |
dc.language | eng | |
dc.publisher | KARGER | |
dc.relation | Nephron Clinical Practice | |
dc.rights | Copyright KARGER | |
dc.rights | restrictedAccess | |
dc.subject | Systemic Lupus Erythematosus Disease Activity Index | |
dc.subject | Anti-C1q | |
dc.subject | Systemic lupus erythematosus | |
dc.subject | Lupus nephritis | |
dc.title | Negative Anti-C1q Antibody Titers May Influence Therapeutic Decisions and Reduce the Number of Renal Biopsies in Systemic Lupus Erythematosus | |
dc.type | Artículos de revistas | |