Artículos de revistas
Optimizing the CAMCOG test in the screening for mild cognitive impairment and incipient dementia: saving time with relevant domains
Fecha
2011Registro en:
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, v.26, n.4, p.403-408, 2011
0885-6230
10.1002/gps.2540
Autor
APRAHAMIAN, Ivan
DINIZ, Breno Satler
IZBICKI, Rafael
RADANOVIC, Marcia
NUNES, Paula Villela
FORLENZA, Orestes Vicente
Institución
Resumen
Objective: To identify the CAMCOG sub-items that best contribute for the identification of patients with mild cognitive impairment (MCI) and incipient Alzheimer`s disease (AD) in clinical practice. Methods: Cross-sectional assessment of 272 older adults (98 MCI, 82 AD, and 92 controls) with a standardized neuropsychological battery and the CAMCOG schedule. Backward logistic regression analysis with diagnosis (MCI and controls) as dependent variable and the sub-items of the CAMCOG as independent variable was carried out to determine the CAMCOG sub-items that predicted the diagnosis of MCI. Results: Lower scores on Language, Memory, Praxis, and Calculation CAMCOG sub-items were significantly associated with the diagnosis of MCI. A composite score obtained by the sum of these scores significantly discriminated MCI patients from comparison groups. This reduced version of the CAMCOG showed similar diagnostic accuracy than the original schedule for the identification of patients with MCI as compared to controls (AUC = 0.80 +/- 0.03 for the reduced CAMCOG; AUC = 0.79 +/- 0.03 for the original CAMCOG). Conclusion: This reduced version of the CAMCOG had similar diagnostic properties as the original CAMCOG and was faster and easier to administer, rendering it more suitable for the screening of subtle cognitive deficits in general clinical practice. Copyright (C) 2010 John Wiley & Sons, Ltd.