Endometrial leukemia inhibitory factor as a predictor of pregnancy after in vitro fertilization

dc.creatorSERAFINI, Paulo
dc.creatorROCHA, Andre M.
dc.creatorOSORIO, Cyntia T.
dc.creatorSILVA, Ismael da
dc.creatorMOTTA, Eduardo L.
dc.creatorBARACAT, Edmund C.
dc.date.accessioned2012-10-19T17:31:43Z
dc.date.accessioned2018-07-04T15:08:27Z
dc.date.available2012-10-19T17:31:43Z
dc.date.available2018-07-04T15:08:27Z
dc.date.created2012-10-19T17:31:43Z
dc.date.issued2008
dc.identifierINTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, v.102, n.1, p.23-27, 2008
dc.identifier0020-7292
dc.identifierhttp://producao.usp.br/handle/BDPI/22359
dc.identifier10.1016/j.ijgo.2007.12.005
dc.identifierhttp://dx.doi.org/10.1016/j.ijgo.2007.12.005
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1619131
dc.description.abstractObjective: To determine whether there is an association between endometrial expression of leukemia inhibitory factor (LIF) in the luteal phase of the menstrual cycle preceding in vitro fertilization (IVF) and treatment outcome. Methods: Biopsy specimens from the endometria of 52 women in the luteal. phase were immunostained against LIF Embryo culture and transfer were done according to standard procedures. Results: Clinical pregnancy occurred in 39% of the women following IVF, and strong endometrial immunohistochemical staining for LIF was associated with pregnancy (P=0.01). The women with a strong LIF expression had a 6.4-fold higher chance of becoming pregnant than those with weaker intensities (P=0.005). Conclusion: Endometrial expression of LIF during the luteal phase can be used as a predictor of IVF success. (C) 2008 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
dc.languageeng
dc.publisherELSEVIER IRELAND LTD
dc.relationInternational Journal of Gynecology & Obstetrics
dc.rightsCopyright ELSEVIER IRELAND LTD
dc.rightsrestrictedAccess
dc.subjectendometrial biopsy
dc.subjectendometrial receptivity
dc.subjectin vitro fertilization
dc.subjectleukemia inhibitory factor
dc.subjectluteal phase
dc.subjecttissue microarray
dc.titleEndometrial leukemia inhibitory factor as a predictor of pregnancy after in vitro fertilization
dc.typeArtículos de revistas


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