dc.creator | HAMANI, Clement | |
dc.creator | EWERTON, Flavio I. S. | |
dc.creator | ALMEIDA, Flavia Marcolin de | |
dc.creator | BONILHA, Saulo M. | |
dc.creator | COVOLAN, Luciene | |
dc.creator | CAVARSAN, Clarissa Fantin | |
dc.creator | BALLESTER, Gerson | |
dc.creator | MELLO, Luiz E. | |
dc.creator | LOZANO, Andres M. | |
dc.date.accessioned | 2012-10-19T17:00:30Z | |
dc.date.accessioned | 2018-07-04T15:03:47Z | |
dc.date.available | 2012-10-19T17:00:30Z | |
dc.date.available | 2018-07-04T15:03:47Z | |
dc.date.created | 2012-10-19T17:00:30Z | |
dc.date.issued | 2009 | |
dc.identifier | STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, v.87, n.3, p.143-147, 2009 | |
dc.identifier | 1011-6125 | |
dc.identifier | http://producao.usp.br/handle/BDPI/21287 | |
dc.identifier | 10.1159/000209294 | |
dc.identifier | http://dx.doi.org/10.1159/000209294 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1618062 | |
dc.description.abstract | Aims: To investigate whether anterior thalamic nucleus (AN) lesions are protective against spontaneous recurrent seizures in the chronic phase of the pilocarpine model of epilepsy. Methods: Two groups of rats were treated with bilateral AN radiofrequency thalamotomies or sham surgery 2 weeks after pilocarpine-induced status epilepticus. After the lesions, animals were videotaped from the 2nd to the 8th week after status epilepticus (total 180 h). Results: During the 6 weeks of observation, no differences in the frequency of spontaneous seizures were found between animals that had bilateral AN lesions (n = 26; 3.1 +/- 0.6 seizures per animal) and controls (n = 25; 3.0 +/- 0.6 seizures per animal; p = 0.8). Conclusions: We conclude that AN thalamotomies were not effective in reducing the frequency of seizures during the chronic phase of the pilocarpine model of epilepsy. Copyright (C) 2009 S. Karger AG, Basel | |
dc.language | eng | |
dc.publisher | KARGER | |
dc.relation | Stereotactic and Functional Neurosurgery | |
dc.rights | Copyright KARGER | |
dc.rights | restrictedAccess | |
dc.subject | Thalamus | |
dc.subject | Deep brain stimulation | |
dc.subject | Thalamotomy | |
dc.subject | Epilepsy | |
dc.subject | Surgery | |
dc.subject | Anterior nucleus | |
dc.title | Bilateral Anterior Thalamic Nucleus Lesions Are Not Protective against Seizures in Chronic Pilocarpine Epileptic Rats | |
dc.type | Artículos de revistas | |