Essential Oil of Thymus vulgaris: Preparation of Pharmaceutical Mouthwash Formulation and In Vitro Evaluation of the Bacterial Plaque-Inhibiting Properties.

dc.creatorSANTOS, Rodolfo I.
dc.creatorPEREIRA, Daniel F. A.
dc.creatorTEODORO, Guilherme R.
dc.creatorCIAMPO, Jose Orestes Del
dc.creatorOGASAWARA, Mario S.
dc.creatorCANETTIERI, Antonio C. V.
dc.creatorKHOURI, Sonia
dc.creatorSALVADOR, Marcos J.
dc.date.accessioned2012-10-19T03:42:03Z
dc.date.accessioned2018-07-04T14:58:03Z
dc.date.available2012-10-19T03:42:03Z
dc.date.available2018-07-04T14:58:03Z
dc.date.created2012-10-19T03:42:03Z
dc.date.issued2010
dc.identifierLATIN AMERICAN JOURNAL OF PHARMACY, v.29, n.6, p.941-947, 2010
dc.identifier0326-2383
dc.identifierhttp://producao.usp.br/handle/BDPI/20143
dc.identifierhttp://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000283811100013&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1616927
dc.description.abstractEssential Oil of Thymus vulgaris: Preparation of Pharmaceutical Mouthwash Formulation and In Vitro Evaluation of the Bacterial Plaque-Inhibiting Properties. The aim of this study was to evaluate the in vitro effect of the essential oil of Thymus vulgaris (thyme) pure or incorporate in a alcohol-free pharmaceutical mouthwash formulation, against Streptococcus mutans (ATCC 25175), being determined the Minimal Inhibitory Concentration (MIC) and the effect in the bacterial plate formation. The MIC value obtained for the essential oil was 100 mu g/mL (1 %). The mouthwash pharmaceutical formulation containing commercial essential oil of T. vulgaris was preparated. Microbiological and macroscopic analysis as well as analyses for MEV confirmed the effectiveness of this new alcohol-free mouthwash formulation containing essential oil of T. vulgaris as agent with plaque-inhibiting properties and possible application in the preventive dentistry. The chemical characterization of the bioactive essential oil was accomplished by CG-MS, being verified the presence of carvacrol, p-cimene and alpha-pinene as major constituents.
dc.languagepor
dc.publisherCOLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES
dc.relationLatin American Journal of Pharmacy
dc.rightsCopyright COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES
dc.rightsclosedAccess
dc.subjectAlcohol-free mouthwash formulation
dc.subjectBacterial plaque-inhibiting properties
dc.subjectThyme
dc.subjectThymus vulgaris
dc.titleEssential Oil of Thymus vulgaris: Preparation of Pharmaceutical Mouthwash Formulation and In Vitro Evaluation of the Bacterial Plaque-Inhibiting Properties.
dc.typeArtículos de revistas


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