dc.creator | ZAGUE, Vivian | |
dc.creator | CHORILLI, Marlus | |
dc.creator | POLACOW, Maria Luiza Ozores | |
dc.creator | PIRES-DE-CAMPOS, Maria Silvia Mariani | |
dc.creator | LEONARDI, Gislaine Ricci | |
dc.date.accessioned | 2012-10-19T03:18:59Z | |
dc.date.accessioned | 2018-07-04T14:56:44Z | |
dc.date.available | 2012-10-19T03:18:59Z | |
dc.date.available | 2018-07-04T14:56:44Z | |
dc.date.created | 2012-10-19T03:18:59Z | |
dc.date.issued | 2010 | |
dc.identifier | JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, v.31, n.6, p.756-759, 2010 | |
dc.identifier | 0193-2691 | |
dc.identifier | http://producao.usp.br/handle/BDPI/19850 | |
dc.identifier | 10.1080/01932690903333051 | |
dc.identifier | http://dx.doi.org/10.1080/01932690903333051 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1616635 | |
dc.description.abstract | In vitro skin permeation of hyaluronidase enzyme and the ultrasound (US) effects on cutaneous permeation of this enzyme were investigated. Diffusion cell technique, porcine skins, buffer solution, and a hydrophilic gel+hyaluronidase (100 TUR/g), were used for study. The experimental groups were: gel+enzyme and gel+enzyme+US. The activity of permeated hyaluronidase was determined by turbydimetric method in spectrophotometer at 400nm. Gel+enzyme group permitted a diffusion of 26.89 +/- 3.82 TUR of hyaluronidase in the total time of 240 minutes. However, the other group did not produce significant differences (p0.05) in the same period (13.68 +/- 5.35 TUR). Hyaluronidase permeation through the skin was verified; however US did not cause increase of this enzyme permeation. | |
dc.language | eng | |
dc.publisher | TAYLOR & FRANCIS INC | |
dc.relation | Journal of Dispersion Science and Technology | |
dc.rights | Copyright TAYLOR & FRANCIS INC | |
dc.rights | restrictedAccess | |
dc.subject | Hyaluronidase | |
dc.subject | in vitro cutaneous permeation | |
dc.subject | ultrasound | |
dc.title | In Vitro Ultrasound Influence on Cutaneous Permeation of Hyaluronidase | |
dc.type | Artículos de revistas | |