In Vitro Ultrasound Influence on Cutaneous Permeation of Hyaluronidase

dc.creatorZAGUE, Vivian
dc.creatorCHORILLI, Marlus
dc.creatorPOLACOW, Maria Luiza Ozores
dc.creatorPIRES-DE-CAMPOS, Maria Silvia Mariani
dc.creatorLEONARDI, Gislaine Ricci
dc.date.accessioned2012-10-19T03:18:59Z
dc.date.accessioned2018-07-04T14:56:44Z
dc.date.available2012-10-19T03:18:59Z
dc.date.available2018-07-04T14:56:44Z
dc.date.created2012-10-19T03:18:59Z
dc.date.issued2010
dc.identifierJOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, v.31, n.6, p.756-759, 2010
dc.identifier0193-2691
dc.identifierhttp://producao.usp.br/handle/BDPI/19850
dc.identifier10.1080/01932690903333051
dc.identifierhttp://dx.doi.org/10.1080/01932690903333051
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1616635
dc.description.abstractIn vitro skin permeation of hyaluronidase enzyme and the ultrasound (US) effects on cutaneous permeation of this enzyme were investigated. Diffusion cell technique, porcine skins, buffer solution, and a hydrophilic gel+hyaluronidase (100 TUR/g), were used for study. The experimental groups were: gel+enzyme and gel+enzyme+US. The activity of permeated hyaluronidase was determined by turbydimetric method in spectrophotometer at 400nm. Gel+enzyme group permitted a diffusion of 26.89 +/- 3.82 TUR of hyaluronidase in the total time of 240 minutes. However, the other group did not produce significant differences (p0.05) in the same period (13.68 +/- 5.35 TUR). Hyaluronidase permeation through the skin was verified; however US did not cause increase of this enzyme permeation.
dc.languageeng
dc.publisherTAYLOR & FRANCIS INC
dc.relationJournal of Dispersion Science and Technology
dc.rightsCopyright TAYLOR & FRANCIS INC
dc.rightsrestrictedAccess
dc.subjectHyaluronidase
dc.subjectin vitro cutaneous permeation
dc.subjectultrasound
dc.titleIn Vitro Ultrasound Influence on Cutaneous Permeation of Hyaluronidase
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución