Retamycin production by immobilized cells of Streptomyces olindensis ICB20 in repeated-batch cultures

dc.creatorPINHEIRO, Iara Reboucas
dc.creatorFACCIOTTI, Maria Candida Reginato
dc.date.accessioned2012-10-19T01:45:35Z
dc.date.accessioned2018-07-04T14:51:21Z
dc.date.available2012-10-19T01:45:35Z
dc.date.available2018-07-04T14:51:21Z
dc.date.created2012-10-19T01:45:35Z
dc.date.issued2008
dc.identifierPROCESS BIOCHEMISTRY, v.43, n.6, p.661-666, 2008
dc.identifier1359-5113
dc.identifierhttp://producao.usp.br/handle/BDPI/18582
dc.identifier10.1016/j.procbio.2008.02.005
dc.identifierhttp://dx.doi.org/10.1016/j.procbio.2008.02.005
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1615376
dc.description.abstractRepeated-batch cultures of Ca-alginate immobilized cells of Streptomyces olindensis ICB20 for retamycin production were carried out in two different bioreactors: a basket-type stirred tank reactor (BSTR) and a bubble column reactor (BCR). Higher average values of retamycin content (R) and productivity (P-R) were achieved in the BSTR cultures (about 1.7 AU and 0.031 AU h(-1), respectively) compared to those obtained in the BCR cultures (about 0.6 AU and 0.012 AU h(-1), respectively). The BCR, on the other hand, presented significantly better operation stability than the BSTR, which makes the former much more promising regarding future industrial applications. (C) 2008 Elsevier Ltd. All rights reserved.
dc.languageeng
dc.publisherELSEVIER SCI LTD
dc.relationProcess Biochemistry
dc.rightsCopyright ELSEVIER SCI LTD
dc.rightsrestrictedAccess
dc.subjectStreptomyces olindensis
dc.subjectimmobilized cells
dc.subjectretamycin
dc.subjectrepeated-batch
dc.subjectbasket-type tank reactor
dc.subjectbubble column reactor
dc.titleRetamycin production by immobilized cells of Streptomyces olindensis ICB20 in repeated-batch cultures
dc.typeArtículos de revistas


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