dc.creatorANTONIO, Selma Gutierrez
dc.creatorFERREIRA, Fabio Furlan
dc.creatorARAUJO, Gabriel Lima Barros
dc.creatorMATOS, Jivaldo do Rosario
dc.creatorPAIVA-SANTOS, Carlos de Oliveira
dc.date.accessioned2012-04-19T15:56:56Z
dc.date.accessioned2018-07-04T14:43:39Z
dc.date.available2012-04-19T15:56:56Z
dc.date.available2018-07-04T14:43:39Z
dc.date.created2012-04-19T15:56:56Z
dc.date.issued2009
dc.identifierPOWDER DIFFRACTION, v.24, n.4, p.337-342, 2009
dc.identifier0885-7156
dc.identifierhttp://producao.usp.br/handle/BDPI/16791
dc.identifier10.1154/1.3257612
dc.identifierhttp://dx.doi.org/10.1154/1.3257612
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1613612
dc.description.abstractTibolone is used for hormone reposition of postmenopause women and isotibolone is considered the major degradation product of tibolone. Isotibolone can also be present in tibolone API raw materials due to some inadequate synthesis. Its presence is then necessary to be identified and quantified in the quality control of both API and drug products. In this work we present the indexing of an isotibolone X-ray diffraction pattern measured with synchrotron light (lambda=1.2407 angstrom) in the transmission mode. The characterization of the isotibolone sample by IR spectroscopy, elemental analysis, and thermal analysis are also presented. The isotibolone crystallographic data are a=6.8066 angstrom, b=20.7350 angstrom, c=6.4489 angstrom, beta=76.428 degrees, V=884.75 angstrom(3), and space group P2(1), rho(o)= 1.187 g cm(-3), Z=2. (C) 2009 International Centre for Diffraction Data. [DOI: 10.1154/1.3257612]
dc.languageeng
dc.publisherJ C P D S-INT CENTRE DIFFRACTION DATA
dc.relationPowder Diffraction
dc.rightsCopyright J C P D S-INT CENTRE DIFFRACTION DATA
dc.rightsopenAccess
dc.subjectisotibolone
dc.subjecthormone
dc.subjectindexing
dc.subjectX-ray powder diffraction
dc.subjectsynchrotron radiation
dc.titleX-ray diffraction data of tibolone Delta(4) isomer (isotibolone)
dc.typeArtículos de revistas


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