Effects of Aflatoxin B(1) and Fumonisin B(1) on the Viability and Induction of Apoptosis in Rat Primary Hepatocytes

dc.creatorRIBEIRO, Deise H. B.
dc.creatorFERREIRA, Fabiane L.
dc.creatorSILVA, Valeria N. da
dc.creatorAQUINO, Simone
dc.creatorCORREA, Benedito
dc.date.accessioned2012-04-18T23:41:02Z
dc.date.accessioned2018-07-04T14:37:58Z
dc.date.available2012-04-18T23:41:02Z
dc.date.available2018-07-04T14:37:58Z
dc.date.created2012-04-18T23:41:02Z
dc.date.issued2010
dc.identifierINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.11, n.4, p.1944-1955, 2010
dc.identifier1422-0067
dc.identifierhttp://producao.usp.br/handle/BDPI/15880
dc.identifier10.3390/ijms11041944
dc.identifierhttp://dx.doi.org/10.3390/ijms11041944
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1612703
dc.description.abstractThe present study evaluated the effect of aflatoxin B(1) (AFB(1)) and fumonisin B(1) (FB(1)) either alone, or in association, on rat primary hepatocyte cultures. Cell viability was assessed by flow cytometry after propidium iodine intercalation. DNA fragmentation and apoptosis were assessed by agarose gel electrophoresis and acridine orange and ethidium bromide staining. At the concentrations of AFB(1) and FB(1) used, the toxins did not decrease cell viability, but did induce apoptosis in a concentration and time-dependent manner.
dc.languageeng
dc.publisherMOLECULAR DIVERSITY PRESERVATION INTERNATIONAL-MDPI
dc.relationInternational Journal of Molecular Sciences
dc.rightsCopyright MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL-MDPI
dc.rightsopenAccess
dc.subjectaflatoxin B(1)
dc.subjectapoptosis
dc.subjectfumonisin B(1)
dc.subjectprimary hepatocytes
dc.titleEffects of Aflatoxin B(1) and Fumonisin B(1) on the Viability and Induction of Apoptosis in Rat Primary Hepatocytes
dc.typeArtículos de revistas


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