Global gene expression profile in myelodysplastic syndromes using SAGE

dc.creatorMENDIBURU, C. F.
dc.creatorSILVA JR., A.
dc.creatorRICCI JR., O.
dc.creatorBONINI-DOMINGOS, C. R.
dc.creatorFETT-CONTE, A. C.
dc.date.accessioned2012-04-18T21:56:19Z
dc.date.accessioned2018-07-04T14:35:37Z
dc.date.available2012-04-18T21:56:19Z
dc.date.available2018-07-04T14:35:37Z
dc.date.created2012-04-18T21:56:19Z
dc.date.issued2008
dc.identifierGENETICS AND MOLECULAR RESEARCH, v.7, n.4, p.1245-1250, 2008
dc.identifier1676-5680
dc.identifierhttp://producao.usp.br/handle/BDPI/15329
dc.identifierhttp://www.geneticsmr.com//year2008/vol7-4/pdf/gmr521.pdf
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1612168
dc.description.abstractThe molecular pathogenesis of myelodysplastic syndromes (MDS) is poorly understood. In order to expand our knowledge of genetic defects in MDS, we determined the overall profile of genes expressed in bone marrow from patients with refractory anemia with excess blasts ( RAEB) by serial analysis of gene expression ( SAGE). The present report describes a partial transcriptome of RAEB bone marrow derived from 56,694 sequenced tags that provides information about expressed gene products. This is the first attempt to determine an overall profile of gene expression specifically in RAEB at diagnosis using SAGE, which should be useful in the understanding of the physiopathology of MDS and in identifying the genes involved.
dc.languageeng
dc.publisherFUNPEC-EDITORA
dc.relationGenetics and Molecular Research
dc.rightsCopyright FUNPEC-EDITORA
dc.rightsopenAccess
dc.subjectSerial analysis of gene expression methodology
dc.subjectMyelodysplastic syndrome
dc.subjectGene expression profile
dc.subjectRefractory anemia with excess blasts
dc.titleGlobal gene expression profile in myelodysplastic syndromes using SAGE
dc.typeArtículos de revistas


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