dc.creator | SOARES-VIEIRA, José A. | |
dc.creator | BILLERBECK, Ana E.C. | |
dc.creator | IWAMURA, Edna S.M. | |
dc.creator | MENDONCA, Berenice B. | |
dc.creator | GUSMÃO, Leonor | |
dc.creator | OTTO, Paulo A. | |
dc.date.accessioned | 2012-03-26T18:24:01Z | |
dc.date.accessioned | 2018-07-04T14:11:27Z | |
dc.date.available | 2012-03-26T18:24:01Z | |
dc.date.available | 2018-07-04T14:11:27Z | |
dc.date.created | 2012-03-26T18:24:01Z | |
dc.date.issued | 2008 | |
dc.identifier | Genetics and Molecular Biology, v.31, n.3, p.651-656, 2008 | |
dc.identifier | 1415-4757 | |
dc.identifier | http://producao.usp.br/handle/BDPI/8966 | |
dc.identifier | 10.1590/S1415-47572008000400009 | |
dc.identifier | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400009 | |
dc.identifier | http://www.scielo.br/pdf/gmb/v31n3/a09v31n3.pdf | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1606974 | |
dc.description.abstract | The haplotypes of seven Y-chromosome STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, and DYS393) were determined in a sample of 634 healthy Brazilian males (190 adult individuals and 222 father-son pairs). The 412 adults were unrelated, and the 222 father-son pairs had their biological relationship confirmed using autosomal STRs (LR > 10,000). Among the 412 adults, a total of 264 different 7-loci haplotypes were identified, 210 of which were unique. The most frequent haplotype was detected in 31 instances, occurring with a frequency of 7.52%. The haplotype diversity index was calculated as 98.83%. Upon transmission of the 1,554 alleles, in 222 father-son pairs, six mutations were observed, with an average overall rate of 3.86 x 10-3 per locus. A haplotype with a duplicated DYS389I locus, and another with duplicated DYS389I, DYS389II, and DYS439 loci were detected in both fathers and their respective sons. | |
dc.language | eng | |
dc.publisher | Sociedade Brasileira de Genética | |
dc.relation | Genetics and Molecular Biology | |
dc.rights | Copyright Sociedade Brasileira de Genética | |
dc.rights | openAccess | |
dc.subject | Y-STR population data | |
dc.subject | São Paulo (Brazil) | |
dc.subject | Mutation rates | |
dc.subject | Duplications | |
dc.title | Population and mutation analysis of Y-STR loci in a sample from the city of São Paulo (Brazil) | |
dc.type | Artículos de revistas | |