Brasil | Artículos de revistas
dc.creatorCHUCRI, Thaís Martins
dc.creatorMONTEIRO, J. M
dc.creatorLIMA, A. R
dc.creatorSALVADORI, M. L. B
dc.creatorKFOURY JUNIOR, José Roberto
dc.creatorMIGLINO, Maria Angélica
dc.date.accessioned2012-03-19T23:04:40Z
dc.date.accessioned2018-07-04T13:44:00Z
dc.date.available2012-03-19T23:04:40Z
dc.date.available2018-07-04T13:44:00Z
dc.date.created2012-03-19T23:04:40Z
dc.date.issued2010
dc.identifierJournal of Reproductive Immunology, Shannon, v. 87, n. 1/2, p. 14-20, 2010
dc.identifier0165-0378
dc.identifierhttp://producao.usp.br/handle/BDPI/1722
dc.identifier10.1016/j.jri.2010.08.062
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1601129
dc.description.abstractFeto-maternal immune transfer occurs via both the placenta in utero and colostrum after birth. The layers between the maternal and fetal circulation systems, known as the placental barrier, regulate immune transfer to the fetus via the placenta. The placental barrier, as well as the type of placental structure, is species specific. The extent of transfer of antibodies from mother to fetus is related to the number of placental barrier layers. Passive immunity via the colostrum is essential in species in which the type of placentation impedes contact between maternal and fetal circulation systems, hindering the transfer of antibodies. In these species, susceptibility to neonatal infections is increased if colostrum is not ingested. Acquired antibodies are of extreme importance for adaptation of the neonate to the extrauterine environment. Based on the aforementioned factors, it was observed that in synepitheliochorial and epitheliochorial placentas immune transfer via the placenta is not possible, except in cases of placental alteration (e.g., placentitis). On the other hand, the mechanism of transfer in endothelial and hemochorial placentas is facilitated compared with other placentas. We conclude that there are no appreciable qualitative differences between the two mechanisms of transfer (placenta and colostrum) and that immune protection in the neonate can be attained by either mechanism
dc.languageeng
dc.publisherShannon
dc.relationJournal of Reproductive Immunology
dc.rightsElsevier Ireland Ltd
dc.rightsrestrictedAccess
dc.subjectPlacenta
dc.subjectPassive immunity
dc.subjectImmune transfer
dc.subjectAntibodies
dc.titleA review of immune transfer by the placenta
dc.typeArtículos de revistas


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