| dc.contributor | Benites Castillo, Santiago | |
| dc.creator | Hurtado Escamilo, Steve Tony | |
| dc.date | 2017-01-04T15:31:40Z | |
| dc.date | 2017-01-04T15:31:40Z | |
| dc.date | 2015 | |
| dc.date.accessioned | 2018-04-27T14:18:33Z | |
| dc.date.available | 2018-04-27T14:18:33Z | |
| dc.identifier | http://dspace.unitru.edu.pe/handle/UNITRU/5423 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1427833 | |
| dc.description | The vaginal microflora of healthy women is dominated by Lactobacillus species, which prevent the growth and invasion of pathogenic bacteria and their decrease is associated with increased incidence of vaginal infections. Objective: To evaluate the effect of vaginal re-colonization by a potential probiotic Lactobacillus strain, Lactobacillus sp. BMP9, in women with bacterial vaginosis (BV). Methods: Women categorized by Nugent criteria: 16 with bacterial vaginosis (Nugent: 7-10 points) and 4 normal (Nugent: 3 points) vaginally received a suspension of 109 CFU / mL of LBP BMP9 for 7 consecutive nights. Vaginal swabs controls were performed on days 1, 7, 15 and 30 post-treatment for categorization according to Nugent. Results: Women with BV showed cure of 81.25% (13/16) (Nugent <7 points), 68.8% (11/16) were normalized (Nugent: ≤ 3 points), and in the normal women group it wasn’t observe negative effects 100% (4/4) at day 30 post-treatment control (t= 7.384, p <0.01) and OR 1.44. Conclusion: Vaginal re-colonization with Lactobacillus sp. BMP9 in women with BV restores the normality of vaginal ecosystem. | |
| dc.description | La microflora vaginal en mujeres sanas está dominada por especies de lactobacilos, que previenen el sobre crecimiento e invasión de bacterias patógenas y su disminución está asociada con un aumento en la incidencia de infecciones vaginales. Objetivo: Evaluar el efecto de la recolonización vaginal por una cepa de lactobacilo probiótico potencial, Lactobacillus sp. BMP9, en mujeres con vaginosis bacteriana. Métodos: Las mujeres categorizadas según criterio de Nugent: 16 con vaginosis bacteriana (VB) (Nugent: 7-10 puntos) y 4 normales (Nugent: 3 puntos) recibieron vaginalmente una suspensión de 109 UFC/mL de LBP BMP9, durante 7 noches consecutivas. Los hisopados vaginales controles fueron realizados los días 1, 7, 15 y 30 post-tratamiento para la categorización según Nugent. Resultados: El 81,25% (13/16) de mujeres con VB mostraron curación (Nugent: <7 puntos), el 68.8% (11/16) se normalizaron (Nugent: ≤ 3 puntos) y en el 100% (4/4) de las mujeres Normales no se observó efectos negativos, al día 30 de control post-tratamiento (t= 7.384, p <0.01) y OR 1,44. Conclusión: La recolonización vaginal con Lactobacillus sp. BMP9 en mujeres con VB restablece la normalidad del ecosistema vaginal | |
| dc.language | spa | |
| dc.publisher | Universidad Nacional de Trujillo | |
| dc.relation | TDBM/045-046/2015; | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights | http://creativecommons.org/licenses/by-nc-nd/2.5/pe/ | |
| dc.source | Universidad Nacional de Trujillo | |
| dc.source | Repositorio Institucional - UNITRU | |
| dc.subject | Vaginosis bacteriana | |
| dc.subject | Probiótico vaginal | |
| dc.subject | Lactobacillus probiótico | |
| dc.title | Efecto de la recolonización vaginal por lactobacillus sp. probiótico potencial en mujeres con vaginosis bacteriana | |
| dc.type | Tesis | |
