Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)This work presents a study of the sorption of a pre-synthesized polysiloxane, poly(methyltetradecylsiloxane)-PMTDS, onto zirconized and titanized-silica particles that results in efficient stationary phases for reversed phase liquid chromatography. The sorbed materials, after 6 days at room temperature without any chemical or physical agent, denominated as self-immobilized stationary phase, present appropriate polymeric layer thicknesses that cover the metalized silica surfaces. The self-immobilization of polymer onto titanized silica particles produces more homogeneous polymeric coatings and stationary phases without silanophilic activity. Zirconized silica-based phases were more chemically resistant, despite their strong retention of basic solutes. In general, the chromatographic performance and chemical stability of metalized silica-based self-immobilized PMTDS phases were similar to conventional chemically bonded stationary phases.27712971304Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)