dc.creatorBierhalz
dc.creatorAndrea C. K.; Westin
dc.creatorCecilia Buzatto; Moraes
dc.creatorAngela Maria
dc.date2016
dc.dateout
dc.date2017-11-13T13:54:22Z
dc.date2017-11-13T13:54:22Z
dc.date.accessioned2018-03-29T06:07:46Z
dc.date.available2018-03-29T06:07:46Z
dc.identifierInternational Journal Of Biological Macromolecules. Elsevier Science Bv, v. 91, p. 496 - 504, 2016.
dc.identifier0141-8130
dc.identifier1879-0003
dc.identifierWOS:000382339200057
dc.identifier10.1016/j.ijbiomac.2016.05.095
dc.identifierhttp://www-sciencedirect-com.ez88.periodicos.capes.gov.br/science/article/pii/S0141813016305098?via%3Dihub
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/329383
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1366408
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionDense and porous chitosan-alginate membranes (1:1 in mass) useful as coverages of skin wounds treated through cell therapy were produced using chitosan of different chain sizes from fungal (white mushrooms) and animal (shrimp shells) sources. Porous materials were obtained by adding the surfactant Poloxamer 188 to the formulations. The influence of chitosan type on membranes physicochemical properties and toxicity to fibroblasts was evaluated. Porosity was noticed to be more pronounced in membranes obtained with fungal chitosan and increased with its molecular mass. These formulations showed the highest values of thickness, roughness, opacity, liquid uptake and water vapor permeability. The membranes were not toxic to fibroblasts, but the lowest cytotoxicity values (0.16-0.21%) were observed for membranes prepared with fungal chitosan in the presence of surfactant. In conclusion, it is possible to replace chitosan from animal sources by chitosan of fungal origin to produce membranes with negligible cytotoxicity while maintaining appropriate physicochemical properties. (C) 2016 Elsevier B.V. All rights reserved.
dc.description91
dc.description496
dc.description504
dc.descriptionFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) from Brazil [2013/23653-0]
dc.descriptionCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) from Brazil [Proex 3665/2014]
dc.descriptionConselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) from Brazil [308871/2012-0]
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageEnglish
dc.publisherElsevier Science BV
dc.publisherAmsterdam
dc.relationInternational Journal of Biological Macromolecules
dc.rightsfechado
dc.sourceWOS
dc.subjectFungal Chitosan
dc.subjectAlginate
dc.subjectMembranes
dc.subjectPoloxamer 188
dc.subjectCytotoxicity
dc.subjectWound Dressings
dc.titleComparison Of The Properties Of Membranes Produced With Alginate And Chitosan From Mushroom And From Shrimp
dc.typeArtículos de revistas


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