Histomorphometric Characterization Of Subgemmal Neurogenous Plaques

dc.creatorAmorim Pellicioli
dc.creatorAna Carolina; Fonseca
dc.creatorFelipe Paiva; Silva
dc.creatorRodrigo Neves; Monteiro Gueiros
dc.creatorLuiz Alcino; de Almeida
dc.creatorOslei Paes; Vargas
dc.creatorPablo Agustin; Lopes
dc.creatorMarcio Ajudarte; Rebelo Pontes
dc.creatorHelder Antonio; Martins
dc.creatorManoela Domingues; Carrard
dc.creatorVincius Coelho; Santos-Silva
dc.creatorAlan Roger
dc.date2017
dc.dateabr
dc.date2017-11-13T13:45:12Z
dc.date2017-11-13T13:45:12Z
dc.date.accessioned2018-03-29T05:59:52Z
dc.date.available2018-03-29T05:59:52Z
dc.identifierOral Surgery Oral Medicine Oral Pathology Oral Radiology. Elsevier Science Inc, v. 123, p. 477 - 481, 2017.
dc.identifier2212-4403
dc.identifier1528-395X
dc.identifierWOS:000398952900014
dc.identifier10.1016/j.oooo.2016.12.014
dc.identifierhttp://www.sciencedirect.com/science/article/pii/S2212440317300019
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/328951
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1365976
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionThe aim of this study was to characterize the histomorphometric features of subgemmal neurogenous plaques (SNPs) to better understand their relationship to surrounding microanatomy included in the tissue biopsy samples of the tongue. Study Design. A 12-year retrospective study on the files of 3 oral pathology centers yielded 28 SNPs. Hematoxylin and eosine stained sections were used for histologic analysis, and immunohistochemical staining for S100 protein was performed to better characterize the neural structures. Slides were scanned and histomorphometric analysis carried out using ImageScope software. Results. Twenty-one women (75%) and 6 men (21.4%) comprised the sample (mean age 46.4 and 49 years, respectively). Twenty cases (71.4%) were juxtaposed to the tongue epithelium and 16 cases (57.1%) were associated with lymphoid tissue. The mean area of the SNPs was 0.160 mm 2, and the mean distance to the overlying epithelium was 0.312 mm. Conclusions. SNPs are normal neural structures located on the posterior border of the tongue that represent a non-neoplastic regional anatomic variation. In some cases, signs or symptoms may be present, and further investigation should be performed. Pathologists should be aware of this entity to avoid confusion with neural lesions.
dc.description123
dc.description4
dc.description477
dc.description481
dc.descriptionState of Sao Paulo Funding Agency (FAPESP)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageEnglish
dc.publisherElsevier Science Inc
dc.publisherNew York
dc.relationOral Surgery Oral Medicine Oral Pathology Oral Radiology
dc.rightsfechado
dc.sourceWOS
dc.subjectSubepithelial Nerve Plexus
dc.subjectJuxtaoral Organ
dc.subjectTaste-buds
dc.subjectChievitz
dc.subjectTongue
dc.titleHistomorphometric Characterization Of Subgemmal Neurogenous Plaques
dc.typeArtículos de revistas


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