The Pharmacological Assay As A Tool To Medicinal Plants Domestication

dc.creatorMontanari
dc.creatorIlio
dc.creatorJr.; Tasca Gois Ruiz
dc.creatorAna Lucia; Parada
dc.creatorCarlos Amilcar; de Carvalho
dc.creatorJoao Ernesto
dc.date2016
dc.date2017-11-13T13:25:05Z
dc.date2017-11-13T13:25:05Z
dc.date.accessioned2018-03-29T05:57:34Z
dc.date.available2018-03-29T05:57:34Z
dc.identifier978-3-95547-034-0
dc.identifier6th International Symposium Breeding Research On Medicinal And Aromatic Plants . Julius Kuhn-inst, v. 453, p. 59 - 61, 2016.
dc.identifier1868-9892
dc.identifierWOS:000385324200019
dc.identifier10.5073/jka.2016.453.019
dc.identifierhttps://ojs.openagrar.de/index.php/JKA/article/view/6489/6089
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/328442
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1365467
dc.descriptionIn Brazil studies with native medicinal plants are usually performed using non-domesticated plants and as a result the genetic variability of wild species could express different levels of active principles changing their therapeutic effect. Based on that, the aim of this study was to demonstrate that extract of different half- sib families Cordia verbenacea (DC), widely used as medicinal plant in Brazil, have different efficacy in the Total Growth Inhibition (TGI) of 5 different human tumor cell lines. Data were statistically analyzed using ANOVA follow by Tuckey test and a heritability estimation of the plant families was performed. The results showed that TGI are different for each plant family according with each human tumor cell line. For instance, extracts obtained from families 3,11 and 12 were more effective to inhibit the U-251 and Ht-29 cell lines compared to the other families, while extracts obtained from the family 32 was more effective against thethe PC-3 line. The heritability coefficient indicated that plant population selection could promote a genetic improvement related to its active principle and their pharmacological effect and could provide the identification of the best families according to their pharmacological efficacy. In conclusion, this study suggests that the domestication of a wild medicinal plant should be better monitored by its pharmacological effect.
dc.description453
dc.description59
dc.description61
dc.description6th International Symposium Breeding Research on Medicinal and Aromatic Plants (BREEDMAP 6)
dc.descriptionJUN 19-23, 2016
dc.descriptionQuedlinburg, GERMANY
dc.description
dc.languageEnglish
dc.publisherJulius Kuhn-Inst
dc.publisherBerlin
dc.relation6TH International Symposium Breeding Research on Medicinal and Aromatic Plants
dc.rightsaberto
dc.sourceWOS
dc.subjectMedicinal Plants
dc.subjectPharmacological Effects
dc.subjectDomestication
dc.titleThe Pharmacological Assay As A Tool To Medicinal Plants Domestication
dc.typeActas de congresos


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