Variation In Phenotype And Virulence Among Enzootic And Panzootic Amphibian Chytrid Lineages

dc.creatorBecker
dc.creatorC. G.; Greenspan
dc.creatorS. E.; Tracy
dc.creatorK. E.; Dash
dc.creatorJ. A.; Lambertini
dc.creatorC.; Jenkinson
dc.creatorT. S.; Leite
dc.creatorD. S.; Toledo
dc.creatorL. F.; Longcore
dc.creatorJ. E.; James
dc.creatorT. Y.; Zamudio
dc.creatorK. R.
dc.date2017
dc.dateabr
dc.date2017-11-13T13:24:32Z
dc.date2017-11-13T13:24:32Z
dc.date.accessioned2018-03-29T05:57:04Z
dc.date.available2018-03-29T05:57:04Z
dc.identifierFungal Ecology. Elsevier Sci Ltd, v. 26, p. 45 - 50, 2017.
dc.identifier1754-5048
dc.identifier1878-0083
dc.identifierWOS:000397836800006
dc.identifier10.1016/j.funeco.2016.11.007
dc.identifierhttp://www.sciencedirect.com/science/article/pii/S1754504816301581
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/328321
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1365346
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionThe Global Panzootic Lineage of the fungus Batrachochytrium dendrobatidis (Bd-GPL) is threatening amphibians worldwide. In contrast, four lineages (Bd-Brazil, Bd-CH, Bd-Cape, and Bd-Korea) that diverged early in the history of Bd have not yet been directly linked to amphibian declines. Bd likely evolves in response to strong selective pressure imposed by hosts and the environment, leading to differences among pathogen phenotypes and genotypes that may directly affect virulence. Here, We report on variation in phenotype, genotype, and virulence of Bd-Brazil and Bd-GPL. Specifically, we (i) used a controlled infection experiment to compare virulence between one Bd-Brazil and three Bd-GPL isolates on a North American amphibian host (Lithobates sylvaticus), (ii) tested for relative phenotypic and genotypic differentiation among Bd isolates from Brazil, and (iii) tested for possible correlations between environmental variables and Bd phenotypes. We found substantial variation in virulence among Bd-GPL isolates and found that our Bd-Brazil isolate showed virulence comparable to an average North American Bd-GPL. North American hosts infected with a Bd-GPL isolate from Panama did not show significant mortality. Bd phenotypes varied significantly across sampling locations; these phenotypes were neither spatially clustered nor correlated with any environmental variables. Additionally, we found a surprising lack of correlation between genotypic divergence and zoospore and zoosporangium sizes in our sample. Although Bd-Brazil was less virulent infecting L. sylvaticus than one Bd-GPL isolate, this endemic lineage still caused-50% mortality in our experimental Ndrth American hosts, This indicates that Bd-Brazil has the potential to kill amphibians if introduced to na ve wild populations. Our findings underscore that characterizing virulence of multiple Bd isolates and lineages is important for understanding the evolutionary history and diversity of Bd. (C) 2016 Elsevier Ltd and British Mycological Society. All rights reserved.
dc.description26
dc.description45
dc.description50
dc.descriptionSao Paulo Research Foundation (FAPESP) [2011/51694-7]
dc.descriptionNational Council for Scientific and Technological Development (CNPq) [405285/2013-2, 302589/2013-9, 300980/2014-0, 312895/2014-3]
dc.descriptionCatalyzing New International Collaborations Grant from the National Science Foundation (NSF) [OISE-1159513]
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageEnglish
dc.publisherElsevier SCI LTD
dc.publisherOxford
dc.relationFungal Ecology
dc.rightsfechado
dc.sourceWOS
dc.subjectDeclines
dc.subjectAnurans
dc.subjectChytridiomycosis
dc.subjectEnvironmental Pressure
dc.titleVariation In Phenotype And Virulence Among Enzootic And Panzootic Amphibian Chytrid Lineages
dc.typeArtículos de revistas


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