Achieving Regio- And Stereo-control In The Fluorination Of Aziridines Under Acidic Conditions

dc.creatorOkoromoba
dc.creatorOtome E.; Li
dc.creatorZhou; Robertson
dc.creatorNicole; Mashuta
dc.creatorMark S.; Couto
dc.creatorUenifer R.; Tormena
dc.creatorClaudio F.; Xu
dc.creatorBo; Hammond
dc.creatorGerald B.
dc.date2016
dc.date2017-11-13T13:16:04Z
dc.date2017-11-13T13:16:04Z
dc.date.accessioned2018-03-29T05:53:27Z
dc.date.available2018-03-29T05:53:27Z
dc.identifierChemical Communications. Royal Soc Chemistry, v. 52, p. 13353 - 13356, 2016.
dc.identifier1359-7345
dc.identifier1364-548X
dc.identifierWOS:000388102800007
dc.identifier10.1039/c6cc07855a
dc.identifierhttp://pubs.rsc.org/en/Content/ArticleLanding/2016/CC/C6CC07855A#!divAbstract
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/327478
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1364503
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionWe developed an efficient fluorination protocol that converts easily accessible aziridines into beta-fluoroamines, which are important motifs in biologically active molecules. In contrast with traditional fluorination approaches, DMPU-HF has shown both higher reactivity and regioselectivity and good functional group tolerance; thus, a wide scope of beta-fluoroamines can now be accessed conveniently. The stereochemical behavior of the ring opening depends on the substitution pattern of the aziridine substrate.
dc.description52
dc.description91
dc.description13353
dc.description13356
dc.descriptionNational Institutes of Health [R15 GM101604-01]
dc.descriptionNational Science Foundation [CHE-1401700]
dc.descriptionNational Science Foundation of China [NSFC-21472018]
dc.descriptionSao Paulo Research Foundation (FAPESP) [2015/08541-6]
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageEnglish
dc.publisherRoyal Soc Chemistry
dc.publisherCambridge
dc.relationChemical Communications
dc.rightsfechado
dc.sourceWOS
dc.subjectHydrogen-fluoride
dc.subjectSynthetic Methods
dc.subjectAmines
dc.subjectReagents
dc.subjectHydrofluorination
dc.subjectDerivatives
dc.subjectConvenient
dc.subjectComplexes
dc.subjectCatalysis
dc.subjectAlkynes
dc.titleAchieving Regio- And Stereo-control In The Fluorination Of Aziridines Under Acidic Conditions
dc.typeArtículos de revistas


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