Artículos de revistas
Sleep Disorders In Machado-joseph Disease
Registro en:
Current Opinion In Psychiatry. Lippincott Williams & Wilkins, v. 29, p. 402 - 408, 2016.
0951-7367
1473-6578
WOS:000385508700014
10.1097/YCO.0000000000000287
Autor
Pedroso
Jose Luiz; Braga-Neto
Pedro; Martinez
Alberto R. M.; Martins Junior
Carlos R.; Rezende Filho
Flavio M.; Sobreira-Neto
Manoel A.; Prado
Lucila B. F.; do Prado
Gilmar F.; Franca Junior
Marcondes C.; Barsottini
Orlando G. P.
Institución
Resumen
Purpose of reviewThis article provides a description on clinical features and pathophysiology of the main sleep disorders observed in Machado-Joseph disease (MJD).Recent findingsPathological studies have clearly demonstrated that degenerative process in MJD is widespread in the nervous system, and not restricted to the cerebellum. Nonmotor manifestations are frequent and may include pain, cramps, dysautonomia, cognitive deficits, psychiatric manifestations, olfactory deficits, fatigue, nutritional issues, and sleep disorders.SummarySleep disorders are frequent in MJD, and include restless legs syndrome, rapid eye movement sleep behavior disorder, excessive daytime sleepiness, insomnia, sleep apnea, periodic limb movements during sleep, parasomnia, and others. Pathophysiological mechanisms related to sleep disorders in Machado-Joseph are complex and poorly understood. Considering that sleep complaints are a treatable condition, recognizing sleep disorders in MJD is relevant. 29 6 402 408