Myotonic Dystrophy Type 1: Frequency Of Ophthalmologic Findings

dc.creatorIkeda
dc.creatorKarin Suzete; Iwabe-Marchese
dc.creatorCristina; Franca
dc.creatorMarcondes Cavalcante
dc.creatorJr.; Nucci
dc.creatorAnamarli; de Carvalho
dc.creatorKeila Monteiro
dc.date2016
dc.datemar
dc.date2017-11-13T11:35:42Z
dc.date2017-11-13T11:35:42Z
dc.date.accessioned2018-03-29T05:49:49Z
dc.date.available2018-03-29T05:49:49Z
dc.identifierArquivos De Neuro-psiquiatria. Assoc Arquivos Neuro- Psiquiatria, v. 74, p. 183 - 188, 2016.
dc.identifier0004-282X
dc.identifier1678-4227
dc.identifierWOS:000374191900002
dc.identifier10.1590/0004-282X20150218
dc.identifierhttp://www.scielo.br/scielo.php?pid=S0004-282X2016000300002&script=sci_arttext
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/326697
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1363703
dc.descriptionThe purpose of the study was to evaluate the frequency of ophthalmologic abnormalities in a cohort of myotonic dystrophy type 1 (DM1) patients and to correlate them with motor function. We reviewed the pathophysiology of cataract and low intraocular pressure (IOP). Method: Patients were included after clinical and laboratory diagnosis and after signed informed consent. They were evaluated by Motor Function Measure scale, Portuguese version (MFM-P) and ophthalmic protocol. Results: We evaluated 42 patients aged 17 to 64 years (mean 40.7 +/- 12.5), 22 of which were men. IOP (n = 41) was reduced in all but one. We found cataract or positivity for surgery in 38 (90.48%) and ptosis in 23 (54.76%). These signs but not IOP were significantly correlated with severity of motor dysfunction. Abnormalities in ocular motility and stereopsis were observed. Conclusion: Cataract and ptosis are frequent in DM1 and associated to motor dysfunction. Reduced IOP is also common, but appears not to be related with motor impairment.
dc.description74
dc.description3
dc.description183
dc.description188
dc.languageEnglish
dc.publisherAssoc Arquivos Neuro- Psiquiatria
dc.publisherSão Paulo
dc.relationArquivos de Neuro-Psiquiatria
dc.rightsaberto
dc.sourceWOS
dc.subjectMyotonic Dystrophy Type 1
dc.subjectCataract
dc.subjectEyelid Ptosis
dc.subjectIntraocular Pressure
dc.subjectMotor Function Measure Scale
dc.subjectPortuguese Version
dc.titleMyotonic Dystrophy Type 1: Frequency Of Ophthalmologic Findings
dc.typeArtículos de revistas


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