Thermal Desorption Modulation For Comprehensive Two-dimensional Gas Chromatography Using A Simple And Inexpensive Segmented-loop Fluidic Interface

dc.creatorMucedola
dc.creatorVanessa; Vieira
dc.creatorLuis C. S.; Pierone
dc.creatorDanilo; Gobbi
dc.creatorAngelo L.; Poppi
dc.creatorRonei J.; Hantao
dc.creatorLeandro W.
dc.date2017
dc.datemar
dc.date2017-11-13T11:34:21Z
dc.date2017-11-13T11:34:21Z
dc.date.accessioned2018-03-29T05:48:38Z
dc.date.available2018-03-29T05:48:38Z
dc.identifierTalanta. Elsevier Science Bv, v. 164, p. 470 - 476, 2017.
dc.identifier0039-9140
dc.identifier1873-3573
dc.identifierWOS:000393244400068
dc.identifier10.1016/j.talanta.2016.12.005
dc.identifierhttp://www.sciencedirect.com/science/article/pii/S0039914016309444
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/326410
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1363416
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionIn this study, we introduce a modulation strategy for comprehensive two-dimensional gas chromatography (GCxGC) by using a simple and consumable-free modulator. This "Do-It-Yourself" interface comprised a 1.0 mx0.25 mm segment of MTX-5 metallic column and a low-cost DC power supply. Thermal desorption modulation (TDM) was attained using a dual-stage heater-based modulator in a novel segmented-loop configuration. TDM was achieved by alternating analyte trapping and thermal desorption. Former process relied on analyte partition to sorbent phase, while latter explored direct resistive heating. Introduction of an intermediate delay segment between the two stages mitigated analyte breakthrough, improving peak symmetry and chromatographic efficiency. This feature was critical to acquire reliable GCxGC modulation using such simple heater-based device. The effects of important modulation variables on 2D separations were investigated, including TDM stage length, dimension of delay loop, and outlet pressure. Significant advances and limitations of proposed TDM strategy were carefully determined. Proposed GCxGC prototype by using an in-oven TDM modulator was successfully applied to a series of challenging matrices, including petroleum distillates, biodiesel, and essential oil. This open-hardware, cost-effective modulator was easy to install and operate, as it circumvented the need for sophisticated components (e.g. moving parts and cooling systems). Therefore, our modulator is a compelling alternative to existing GCxGC solutions to operate in resource-limited laboratories.
dc.description164
dc.description470
dc.description476
dc.descriptionSao Paulo Research Foundation [AP.R 2015/05059-9]
dc.descriptionPetrobras [2014/00228-4]
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageEnglish
dc.publisherElsevier Science BV
dc.publisherAmsterdam
dc.relationTalanta
dc.rightsfechado
dc.sourceWOS
dc.subjectChemical Education
dc.subjectMass Spectrometry
dc.subjectMultidimensional Gas Chromatography
dc.subjectPetroleum
dc.subjectPoly(dimethylsiloxane)
dc.subjectVolatile Organic Compound
dc.titleThermal Desorption Modulation For Comprehensive Two-dimensional Gas Chromatography Using A Simple And Inexpensive Segmented-loop Fluidic Interface
dc.typeArtículos de revistas


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