Effect Of Resveratrol On Periodontal Pathogens During Experimental Periodontitis In Rats

dc.creatorCirano
dc.creatorFabiano Ribeiro; Casarin
dc.creatorRenato Correa Viana; Ribeiro
dc.creatorFernanda Vieira; Casati
dc.creatorMarcio Zaffalon; Pimentel
dc.creatorSuzana Peres; Taiete
dc.creatorTiago; Bernardi
dc.creatorMaria Martha
dc.date2016
dc.date2017-08-30T17:37:26Z
dc.date2017-08-30T17:37:26Z
dc.date.accessioned2018-03-29T05:30:14Z
dc.date.available2018-03-29T05:30:14Z
dc.identifierBrazilian Oral Research . Sociedade Brasileira De Pesquisa Odontológica - Sbpqo, v. 30, n. 1, p.
dc.identifier1806-8324
dc.identifierS1806-83242016000100318
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242016000100318&lng=en&tlng=en
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/324778
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1358996
dc.descriptionThe objective of this study was to investigate the antibacterial effect of resveratrol against putative periodontal pathogens during the progression of experimental periodontitis in rats. Periodontitis was induced in rats in one of the first molars chosen to receive a ligature. Animals were assigned to one of two groups: daily administration of the placebo solution (control group, n = 12) or 10 mg/Kg of resveratrol (RESV group, n = 12). The therapies were administered systemically for 30 days, for 19 days before periodontitis induction and then for another 11 days. Then, the presence and concentrations of Porphyromonas gingivalis, Tannerella forsythia and Aggregatibacter actinomycetemcomitans in the cotton ligatures collected from the first molars were evaluated using real-time PCR. Inter-group comparisons of the microbiological outcomes revealed that no differences were detected for P. gingivalis, T. forsythia and A. actinomycetemcomitans levels (p > 0.05). Continuous use of resveratrol did not promote additional benefits in microbiological outcomes during experimental periodontitis in rats.
dc.description30
dc.description1
dc.languageIngles
dc.publisherSociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.relationBrazilian Oral Research
dc.rightsaberto
dc.sourceScielo
dc.subjectResveratrol
dc.subjectPeriodontitis
dc.subjectAlveolar Bone Loss
dc.subjectAnti-inflammatory Agents
dc.subjectAnti-bacterial Agents
dc.titleEffect Of Resveratrol On Periodontal Pathogens During Experimental Periodontitis In Rats
dc.typeArtículos de revistas


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